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Comparative Genetics: Synergizing Human and NOD Mouse Studies for Identifying Genetic Causation of Type 1 Diabetes

Although once widely anticipated to unlock how human type 1 diabetes (T1D) develops, extensive study of the nonobese diabetic (NOD) mouse has failed to yield effective treatments for patients with the disease. This has led many to question the usefulness of this animal model. While criticism about t...

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Autori principali: Driver, John P., Chen, Yi-Guang, Mathews, Clayton E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: SBDR - Society for Biomedical Diabetes Research 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3740689/
https://ncbi.nlm.nih.gov/pubmed/23804259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1900/RDS.2012.9.169
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