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A locus on mouse Chromosome 13 inversely regulates CD1d expression and the development of invariant natural killer T-cells

Invariant natural killer T (iNKT)-cell development is controlled by many polymorphic genes present in commonly used mouse inbred strains. Development of type 1 diabetes (T1D) in NOD mice partly results from their production of fewer iNKT-cells compared to non-autoimmune prone control strains includi...

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Detalhes bibliográficos
Publicado no:Genes Immun
Main Authors: Tsaih, Shirng-Wern, Presa, Maximiliano, Khaja, Shamim, Ciecko, Ashley E., Serreze, David V., Chen, Yi-Guang
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4409484/
https://ncbi.nlm.nih.gov/pubmed/25654212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gene.2014.81
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