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Genetic control of murine invariant natural killer T-cells maps to multiple type 1 diabetes regions

Reduced frequency of invariant natural killer T (iNKT)-cells has been indicated as a contributing factor to type 1 diabetes (T1D) development in NOD mice. To further understand the genetic basis of the defect, we generated (NOD X ICR)F2 mice to map genes that control iNKT-cell development. We determ...

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Detalhes bibliográficos
Main Authors: Tsaih, Shirng-Wern, Khaja, Shamim, Ciecko, Ashley E., MacKinney, Erin, Chen, Yi-Guang
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3766462/
https://ncbi.nlm.nih.gov/pubmed/23719031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gene.2013.32
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