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Subcongenic analyses reveal complex interactions between distal Chromosome 4 genes controlling diabetogenic B cells and CD4 T cells in NOD mice.

Autoimmune Type 1 Diabetes (T1D) in humans and NOD mice results from interactions between multiple susceptibility genes (termed Idd) located within and outside the MHC. Despite sharing ~88% of their genome with NOD, including the H2(g7) MHC haplotype and other important Idd genes, the closely relate...

詳細記述

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書誌詳細
主要な著者: Stolp, Jessica, Chen, Yi-Guang, Cox, Selwyn L., Henck, Vivien, Zhang, Wenyu, Tsaih, Shirng-Wern, Chapman, Harold, Stearns, Timothy, Serreze, David V., Silveira, Pablo A.
フォーマット: Artigo
言語:Inglês
出版事項: 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3401322/
https://ncbi.nlm.nih.gov/pubmed/22732593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1200120
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