Thematic Selection: Strategies of Current Drugs and Alternative Treatments for Neurodegenerative Diseases

Por Wang, Xiao-Ping, Chen, Hong-Zhuan
Publicado no Curr Neuropharmacol (2016)

AChE Inhibition-based Multi-target-directed Ligands, a Novel Pharmacological Approach for the Symptomatic and Disease-modifying Therapy of Alzheimer's Disease

Por Wang, Yu, Wang, Hao, Chen, Hong-zhuan
Publicado no Curr Neuropharmacol (2016)

Activation of muscarinic receptors inhibits glutamate-induced GSK-3β overactivation in PC12 cells

Por Ma, Ke, Yang, Li-min, Chen, Hong-zhuan, Lu, Yang
Publicado em 2013

(1R,3S,5R,6S)-6-Acet­oxy-3-(4-methyl­phenyl­sulfon­yloxy)tropane

Por Yang, Li-Min, Zhu, Liang, Niu, Yin-Yao, Chen, Hong-Zhuan, Lu, Yang
Publicado em 2008

Cholesterol Regulates μ-Opioid Receptor-Induced β-Arrestin 2 Translocation to Membrane Lipid Rafts

Por Qiu, Yu, Wang, Yan, Law, Ping-Yee, Chen, Hong-Zhuan, Loh, Horace H.
Publicado em 2011

Activation of M1 mAChRs by lesatropane rescues glutamate neurotoxicity in PC12 cells via PKC-mediated phosphorylation of ERK1/2.

Por Ma, Ke, Yang, Zhi-Hui, Yang, Li-Min, Chen, Hong-Zhuan, Lu, Yang
Publicado no Bosn J Basic Med Sci (2013)

A Systems View of the Differences between APOE ε4 Carriers and Non-carriers in Alzheimer’s Disease

Por Jiang, Shan, Tang, Ling, Zhao, Na, Yang, Wanling, Qiu, Yu, Chen, Hong-Zhuan
Publicado no Front Aging Neurosci (2016)

(1R,3S,5R,6S)-6-Acet­oxy-8-methyl-3-(p-tolyl­sulfon­yloxy)-8-azoniabicyclo­[3.2.1]octane (2R,3R)-2,3-bis­(benzo­yloxy)-3-carboxy­propanoate

Por Yang, Li-Min, Xie, Yi-Fan, Gu, Ya-Fang, Chen, Hong-Zhuan, Lu, Yang
Publicado em 2009

Homologous recombination-based adenovirus vector system for tumor cell-specific gene delivery

Por Lu, Qin, Ye, Xun, Liu, Fang, Zhao, Yi, Qin, Jie, Liang, Min, Fang, Chao, Chen, Hong-Zhuan
Publicado em 2013

Role of FK506 binding protein 12 in morphine-induced μ-opioid receptor internalization and desensitization

Por Yan, Ying-Hui, Wang, Yan, Zhao, Lan-Xue, Jiang, Shan, Loh, Horace H., Law, Ping-Yee, Chen, Hong-Zhuan, Qiu, Yu
Publicado em 2014

Modulation of mTOR Activity by μ‐Opioid Receptor is Dependent upon the Association of Receptor and FK506‐Binding Protein 12

Por Wang, Yan, Ge, Yan‐Hui, Wang, Yan‐Xia, Liu, Ting, Law, Ping‐Yee, Loh, Horace H., Chen, Hong‐Zhuan, Qiu, Yu
Publicado no CNS Neurosci Ther (2015)

The activation of M3 mAChR in airway epithelial cells promotes IL-8 and TGF-β1 secretion and airway smooth muscle cell migration

Por Lu, Juan-Juan, Xu, Guang-Ni, Yu, Ping, Song, Yun, Wang, Xiao-Lin, Zhu, Liang, Chen, Hong-Zhuan, Cui, Yong-Yao
Publicado no Respir Res (2016)

Crystal structure of FabZ-ACP complex reveals a dynamic seesaw-like catalytic mechanism of dehydratase in fatty acid biosynthesis

Por Zhang, Lin, Xiao, Jianfeng, Xu, Jianrong, Fu, Tianran, Cao, Zhiwei, Zhu, Liang, Chen, Hong-Zhuan, Shen, Xu, Jiang, Hualiang, Zhang, Liang
Publicado no Cell Res (2016)

Role of α7-nicotinic acetylcholine receptor in nicotine-induced invasion and epithelial-to-mesenchymal transition in human non-small cell lung cancer cells

Por Zhang, Chun, Ding, Xu-Ping, Zhao, Qing-Nan, Yang, Xin-Jie, An, Shi-Min, Wang, Hao, Xu, Lu, Zhu, Liang, Chen, Hong-Zhuan
Publicado no Oncotarget (2016)

Interleukin-6 identified as an important factor in hypoxia- and aldehyde dehydrogenase-based gefitinib adaptive resistance in non-small cell lung cancer cells

Por An, Shi-Min, Lei, Hui-Min, Ding, Xu-Ping, Sun, Fan, Zhang, Chun, Tang, Ya-Bin, Chen, Hong-Zhuan, Shen, Ying, Zhu, Liang
Publicado no Oncol Lett (2017)

Adrenergic DNA damage of embryonic pluripotent cells via β2 receptor signalling

Por Sun, Fan, Ding, Xu-Ping, An, Shi-Min, Tang, Ya-Bin, Yang, Xin-Jie, Teng, Lin, Zhang, Chun, Shen, Ying, Chen, Hong-Zhuan, Zhu, Liang
Publicado no Sci Rep (2015)

Autocrine glutamatergic transmission for the regulation of embryonal carcinoma stem cells

Por Teng, Lin, Lei, Hui-Min, Sun, Fan, An, Shi-Min, Tang, Ya-Bin, Meng, Shuang, Wang, Cong-Hui, Shen, Ying, Chen, Hong-Zhuan, Zhu, Liang
Publicado no Oncotarget (2016)

FK506-Binding Protein 12 Modulates μ-Opioid Receptor Phosphorylation and Protein Kinase Cε–Dependent Signaling by Its Direct Interaction with the Receptor

Por Qiu, Yu, Zhao, Wei, Wang, Yan, Xu, Jian-Rong, Huie, Eddie, Jiang, Shan, Yan, Ying-Hui, Loh, Horace H., Chen, Hong-Zhuan, Law, Ping-Yee
Publicado em 2014

mAChRs activation induces epithelial-mesenchymal transition on lung epithelial cells

Por Yang, Kai, Song, Yun, Tang, Ya-Bing, Xu, Zu-Peng, Zhou, Wei, Hou, Li-Na, Zhu, Liang, Yu, Zhi-Hua, Chen, Hong-Zhuan, Cui, Yong-Yao
Publicado em 2014

DN-01 BYPASSING GLIOBLASTOMA RESISTANCE TO EGFR INHIBITORS BY SYNTHETIC LETHALITY

Por Chen, Clark, Shen, Ying, Nitta, Masayuki, Futalan, Diahnn, Taich, Zack, Treiber, Jeffrey, Stevens, Deanna, Chen, Hong-Zhuan, Carter, Bob, Esashi, Fumiko, Sarkaria, Jann, Furnari, Frank, Cavenee, Webster, Desai, Arshad
Publicado em 2014