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Activation of muscarinic receptors inhibits glutamate-induced GSK-3β overactivation in PC12 cells
AIM: To investigate the actions of the muscarinic agonist carbachol on glutamate-induced neurotoxicity in PC12 cells, and the underlying mechanisms. METHODS: PC12 cells were treated with different concentrations of glutamate for 24 or 48 h. The cell viability was measured using MTT assay, and the ex...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4002616/ https://ncbi.nlm.nih.gov/pubmed/23685950 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2013.42 |
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