Activation of muscarinic receptors inhibits glutamate-induced GSK-3β overactivation in PC12 cells

AIM: To investigate the actions of the muscarinic agonist carbachol on glutamate-induced neurotoxicity in PC12 cells, and the underlying mechanisms. METHODS: PC12 cells were treated with different concentrations of glutamate for 24 or 48 h. The cell viability was measured using MTT assay, and the ex...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Ma, Ke, Yang, Li-min, Chen, Hong-zhuan, Lu, Yang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2013
Schlagworte:
Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4002616/
https://ncbi.nlm.nih.gov/pubmed/23685950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2013.42
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