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Interleukin-6 identified as an important factor in hypoxia- and aldehyde dehydrogenase-based gefitinib adaptive resistance in non-small cell lung cancer cells

Gefitinib resistance and relapse of the disease were the greatest challenges facing clinical therapy of non-small-cell lung cancer (NSCLC). Of note, regarding the hypoxia condition in solid tumor tissues in vivo, roles of hypoxia in gefitinib adaptive resistance and its association with lung cancer...

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Detalhes bibliográficos
Publicado no:Oncol Lett
Main Authors: An, Shi-Min, Lei, Hui-Min, Ding, Xu-Ping, Sun, Fan, Zhang, Chun, Tang, Ya-Bin, Chen, Hong-Zhuan, Shen, Ying, Zhu, Liang
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5588073/
https://ncbi.nlm.nih.gov/pubmed/28927099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.6613
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