Getting a grip on calcium regulation

Por Blaustein, Mordecai P., Charpentier, Thomas H., Weber, David J.
Publicado em 2007

Auto-inhibition and phosphorylation-induced activation of PLC-γ isozymes

Por Hajicek, Nicole, Charpentier, Thomas H., Rush, Jeremy R., Harden, T. Kendall, Sondek, John
Publicado em 2013

Membrane-induced Allosteric Control of Phospholipase C-β Isozymes

Por Charpentier, Thomas H., Waldo, Gary L., Barrett, Matthew O., Huang, Weigang, Zhang, Qisheng, Harden, T. Kendall, Sondek, John
Publicado em 2014

The effects of the CapZ peptide (TRTK-12) binding to S100B-Ca(2+) as examined by NMR and X-ray crystallography

Por Charpentier, Thomas H., Thompson, Laura E., Liriano, Melissa A., Varney, Kristen M., Wilder, Paul T., Pozharski, Edwin, Toth, Eric A., Weber, David J.
Publicado em 2010

Potent and Selective Peptide-based Inhibition of the G Protein Gα(q)

Por Charpentier, Thomas H., Waldo, Gary L., Lowery-Gionta, Emily G., Krajewski, Krzysztof, Strahl, Brian D., Kash, Thomas L., Harden, T. Kendall, Sondek, John
Publicado no J Biol Chem (2016)

Divalent Metal Ion Complexes of S100B in the Absence and Presence of Pentamidine

Por Charpentier, Thomas H., Wilder, Paul T., Liriano, Melissa A., Varney, Kristen M., Pozharski, Edwin, MacKerell, Alexander D., Coop, Andrew, Toth, Eric A., Weber, David J.
Publicado em 2008

Small Molecules Bound to Unique Sites in the Target Protein Binding Cleft of Calcium-Bound S100B As Characterized by Nuclear Magnetic Resonance and X-ray Crystallography

Por Charpentier, Thomas H., Wilder, Paul T., Liriano, Melissa A., Varney, Kristen M., Zhong, Shijun, Coop, Andrew, Pozharski, Edwin, MacKerell, Alexander D., Toth, Eric A., Weber, David J.
Publicado em 2009

In vitro screening and structural characterization of inhibitors of the S100B-p53 interaction

Por Wilder, Paul T, Charpentier, Thomas H, Liriano, Melissa A, Gianni, Kira, Varney, Kristen M, Pozharski, Edwin, Coop, Andrew, Toth, Eric A, MacKerell, Alex D, Weber, David J
Publicado em 2010

Structure of Ca(2+)-Bound S100A4 and Its Interaction with Peptides Derived from Nonmuscle Myosin-IIA

Por Malashkevich, Vladimir N., Varney, Kristen M., Garrett, Sarah C., Wilder, Paul T., Knight, David, Charpentier, Thomas H., Ramagopal, Udupi A., Almo, Steven C., Weber, David J., Bresnick, Anne R.
Publicado em 2008

Small Molecule Inhibitors of Ca(2+)-S100B Reveal Two Protein Conformations

Por Cavalier, Michael C., Ansari, Mohd. Imran, Pierce, Adam D., Wilder, Paul T., McKnight, Laura E., Raman, E. Prabhu, Neau, David B., Bezawada, Padmavani, Alasady, Milad J., Charpentier, Thomas H., Varney, Kristen M., Toth, Eric A., MacKerell, Alexander D., Coop, Andrew, Weber, David J.
Publicado no J Med Chem (2016)

A Cell-Permeable Inhibitor to Trap Gα(q) Proteins in the Empty Pocket Conformation

Por Schmitz, Anna-Lena, Schrage, Ramona, Gaffal, Evelyn, Charpentier, Thomas H., Wiest, Johannes, Hiltensperger, Georg, Morschel, Julia, Hennen, Stephanie, Häußler, Daniela, Horn, Velten, Wenzel, Daniela, Grundmann, Manuel, Büllesbach, Katrin M., Schröder, Ralf, Brewitz, H. Henning, Schmidt, Johannes, Gomeza, Jesús, Galés, Céline, Fleischmann, Bernd K., Tüting, Thomas, Imhof, Diana, Tietze, Daniel, Gütschow, Michael, Holzgrabe, Ulrike, Sondek, John, Harden, T. Kendall, Mohr, Klaus, Kostenis, Evi
Publicado no Chem Biol (2014)

The experimental power of FR900359 to study Gq-regulated biological processes

Por Schrage, Ramona, Schmitz, Anna-Lena, Gaffal, Evelyn, Annala, Suvi, Kehraus, Stefan, Wenzel, Daniela, Büllesbach, Katrin M., Bald, Tobias, Inoue, Asuka, Shinjo, Yuji, Galandrin, Ségolène, Shridhar, Naveen, Hesse, Michael, Grundmann, Manuel, Merten, Nicole, Charpentier, Thomas H., Martz, Matthew, Butcher, Adrian J., Slodczyk, Tanja, Armando, Sylvain, Effern, Maike, Namkung, Yoon, Jenkins, Laura, Horn, Velten, Stößel, Anne, Dargatz, Harald, Tietze, Daniel, Imhof, Diana, Galés, Céline, Drewke, Christel, Müller, Christa E., Hölzel, Michael, Milligan, Graeme, Tobin, Andrew B., Gomeza, Jesús, Dohlman, Henrik G., Sondek, John, Harden, T. Kendall, Bouvier, Michel, Laporte, Stéphane A., Aoki, Junken, Fleischmann, Bernd K., Mohr, Klaus, König, Gabriele M., Tüting, Thomas, Kostenis, Evi
Publicado no Nat Commun (2015)