Divalent Metal Ion Complexes of S100B in the Absence and Presence of Pentamidine

As part of an effort to inhibit S100B, structures of pentamidine (Pnt) bound to Ca(2+)-loaded and Zn(2+),Ca(2+)-loaded S100B were determined by X-ray crystallography at 2.15 Å (R(free) = 0.266) and 1.85 Å (R(free) = 0.243) resolution, respectively. These data were compared to X-ray structures solved...

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Main Authors: Charpentier, Thomas H., Wilder, Paul T., Liriano, Melissa A., Varney, Kristen M., Pozharski, Edwin, MacKerell, Alexander D., Coop, Andrew, Toth, Eric A., Weber, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2636698/
https://ncbi.nlm.nih.gov/pubmed/18602402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.06.047
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