Membrane-induced Allosteric Control of Phospholipase C-β Isozymes

All peripheral membrane proteins must negotiate unique constraints intrinsic to the biological interface of lipid bilayers and the cytosol. Phospholipase C-β (PLC-β) isozymes hydrolyze the membrane lipid phosphatidylinositol 4,5-bisphosphate (PIP(2)) to propagate diverse intracellular responses that...

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Detalhes bibliográficos
Main Authors: Charpentier, Thomas H., Waldo, Gary L., Barrett, Matthew O., Huang, Weigang, Zhang, Qisheng, Harden, T. Kendall, Sondek, John
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4207972/
https://ncbi.nlm.nih.gov/pubmed/25193662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.586784
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