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A Fluorogenic, Small Molecule Reporter for Mammalian Phospholipase C Isozymes
Phospholipase C isozymes (PLCs) catalyze the conversion of the membrane lipid phosphatidylinositol 4,5-bisphosphate (PIP(2)) into two second messengers, inositol 1,4,5-trisphosphate and diacylglycerol. This family of enzymes are key signaling proteins that regulate the physiological responses of man...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3312000/ https://ncbi.nlm.nih.gov/pubmed/21158426 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb100308n |
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