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Small Molecule Inhibitors of Phospholipase C from a Novel High-throughput Screen
Phospholipase C (PLC) isozymes are important signaling molecules, but few small molecule modulators are available to pharmacologically regulate their function. With the goal of developing a general approach for identification of novel PLC inhibitors, we developed a high-throughput assay based on the...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Biochemistry and Molecular Biology
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3581404/ https://ncbi.nlm.nih.gov/pubmed/23297405 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.422501 |
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