Hydrogen-bond formation of the residue in H-loop of the nucleotide binding domain 2 with the ATP in this site and/or other residues of multidrug resistance protein MRP1 plays a cru...

Por Yang, Runying, Chang, Xiu-bao
Publicado em 2006

What is the functional role of the thalidomide binding protein cereblon?

Por Chang, Xiu-bao, Stewart, A. Keith
Publicado em 2011

The hydroxyl group of S685 in Walker A motif and the carboxyl group of D792 in Walker B motif of NBD1 play a crucial role for multidrug resistance protein folding and function

Por Yang, Runying, Scavetta, Robert, Chang, Xiu-bao
Publicado em 2007

Infection of H69AR cells with retroviral particles harboring interfering RNAi significantly reduced the multidrug resistance of these small cell lung cancer cells

Por Palaniyandi, Kanagaraj, Zhao, Qing, Chang, Xiu-Bao
Publicado em 2011

Interaction between the Bound Mg•ATP and the Walker A Serine Residue in NBD2 of Multidrug Resistance-Associated Protein MRP1 Plays a Crucial Role for the ATP-Dependent Leukotriene...

Por Yang, Runying, Scavetta, Robert, Chang, Xiu-bao
Publicado em 2008

CRISPR/Cas9-Mediated Three Nucleotide Insertion Corrects a Deletion Mutation in MRP1/ABCC1 and Restores Its Proper Folding and Function

Por Xu, Qinqin, Hou, Yue-xian, Chang, Xiu-bao
Publicado no Mol Ther Nucleic Acids (2017)

The non-hydrolytic pathway of cystic fibrosis transmembrane conductance regulator ion channel gating

Por Aleksandrov, Andrei A, Chang, Xiu-bao, Aleksandrov, Luba, Riordan, John R
Publicado em 2000

Human Breast Cancer Stem Cells Have Significantly Higher Rate of Clathrin-Independent and Caveolin-Independent Endocytosis than the Differentiated Breast Cancer Cells

Por Palaniyandi, Kanagaraj, Pockaj, Barbara A., Gendler, Sandra J., Chang, Xiu-Bao
Publicado em 2012

Replacement of the positively charged Walker A lysine residue with a hydrophobic leucine residue and conformational alterations caused by this mutation in MRP1 impair ATP binding a...

Por Buyse, Frederic, Hou, Yue-xian, Vigano, Catherine, Zhao, Qing, Ruysschaert, Jean-Marie, Chang, Xiu-bao
Publicado em 2006

Dibasic protein kinase A sites regulate bursting rate and nucleotide sensitivity of the cystic fibrosis transmembrane conductance regulator chloride channel

Por Mathews, Ceri J, Tabcharani, Joseph A, Chang, Xiu-Bao, Jensen, Timothy J, Riordan, John R, Hanrahan, John W
Publicado em 1998

Effects of Putative Catalytic Base Mutation E211Q on ABCG2-Mediated Methotrexate Transport

Por Hou, Yue-xian, Li, Chang-Zhong, Palaniyandi, Kanagaraj, Magtibay, Paul M., Homolya, Laszlo, Sarkadi, Balazs, Chang, Xiu-bao
Publicado em 2009

Glutamine residues in Q-loops of multidrug resistance protein MRP1 contribute to ATP binding via interaction with metal cofactor

Por Yang, Runying, Hou, Yue-xian, Campbell, Chase A., Palaniyandi, Kanagaraj, Zhao, Qing, Bordner, Andrew J., Chang, Xiu-bao
Publicado em 2011

Potential sites of CFTR activation by tyrosine kinases

Por Billet, Arnaud, Jia, Yanlin, Jensen, Timothy J., Hou, Yue-Xian, Chang, Xiu-Bao, Riordan, John R., Hanrahan, John W.
Publicado no Channels (Austin) (2015)

Endocytic Trafficking Routes of Wild Type and ΔF508 Cystic Fibrosis Transmembrane Conductance Regulator

Por Gentzsch, Martina, Chang, Xiu-Bao, Cui, Liying, Wu, Yufeng, Ozols, Victor V., Choudhury, Amit, Pagano, Richard E., Riordan, John R.
Publicado em 2004

Role of N-linked oligosaccharides in the biosynthetic processing of the cystic fibrosis membrane conductance regulator

Por Chang, Xiu-bao, Mengos, April, Hou, Yue-xian, Cui, Liying, Jensen, Timothy J., Aleksandrov, Andrei, Riordan, John R., Gentzsch, Martina
Publicado em 2008

Stimulatory and inhibitory protein kinase C consensus sequences regulate the cystic fibrosis transmembrane conductance regulator

Por Chappe, Valerie, Hinkson, Deborah A., Howell, L. Daniel, Evagelidis, Alexandra, Liao, Jie, Chang, Xiu-Bao, Riordan, John R., Hanrahan, John W.
Publicado em 2004

Permeability of Wild-Type and Mutant Cystic Fibrosis Transmembrane Conductance Regulator Chloride Channels to Polyatomic Anions

Por Linsdell, Paul, Tabcharani, Joseph A., Rommens, Johanna M., Hou, Yue-Xian, Chang, Xiu-Bao, Tsui, Lap-Chee, Riordan, John R., Hanrahan, John W.
Publicado em 1997

Expression of the cereblon binding protein argonaute 2 plays an important role for multiple myeloma cell growth and survival

Por Xu, Qinqin, Hou, Yue-xian, Langlais, Paul, Erickson, Patrick, Zhu, James, Shi, Chang-Xin, Luo, Moulun, Zhu, Yuanxiao, Xu, Ye, Mandarino, Lawrence J., Stewart, Keith, Chang, Xiu-bao
Publicado no BMC Cancer (2016)

Cereblon expression is required for the antimyeloma activity of lenalidomide and pomalidomide

Por Zhu, Yuan Xiao, Braggio, Esteban, Shi, Chang-Xin, Bruins, Laura A., Schmidt, Jessica E., Van Wier, Scott, Chang, Xiu-Bao, Bjorklund, Chad C., Fonseca, Rafael, Bergsagel, P. Leif, Orlowski, Robert Z., Stewart, A. Keith
Publicado em 2011

Identification of cereblon-binding proteins and relationship with response and survival after IMiDs in multiple myeloma

Por Zhu, Yuan Xiao, Braggio, Esteban, Shi, Chang-Xin, Kortuem, K. Martin, Bruins, Laura A., Schmidt, Jessica E., Chang, Xiu-Bao, Langlais, Paul, Luo, Moulun, Jedlowski, Patrick, LaPlant, Betsy, Laumann, Kristina, Fonseca, Rafael, Bergsagel, P. Leif, Mikhael, Joseph, Lacy, Martha, Champion, Mia D., Stewart, A. Keith
Publicado em 2014