Identification of cereblon-binding proteins and relationship with response and survival after IMiDs in multiple myeloma

Cereblon (CRBN) mediates immunomodulatory drug (IMiD) action in multiple myeloma (MM). Using 2 different methodologies, we identified 244 CRBN binding proteins and established relevance to MM biology by changes in their abundance after exposure to lenalidomide. Proteins most reproducibly binding CRB...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Zhu, Yuan Xiao, Braggio, Esteban, Shi, Chang-Xin, Kortuem, K. Martin, Bruins, Laura A., Schmidt, Jessica E., Chang, Xiu-Bao, Langlais, Paul, Luo, Moulun, Jedlowski, Patrick, LaPlant, Betsy, Laumann, Kristina, Fonseca, Rafael, Bergsagel, P. Leif, Mikhael, Joseph, Lacy, Martha, Champion, Mia D., Stewart, A. Keith
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society of Hematology 2014
Pynciau:
Lymphoid Neoplasia
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4110660/
https://ncbi.nlm.nih.gov/pubmed/24914135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-02-557819
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg