Just How Critical is Epithelial-to-Mesenchymal Transition (EMT) to Metastatic Dissemination?

per LA, Torre-Healy, Chan, Chia-Hsin
Publicat a J Pharmacol Clin Trials (2019)

Tackling Cancer Stem Cells via Inhibition of EMT Transcription Factors

per Mladinich, Megan, Ruan, Diane, Chan, Chia-Hsin
Publicat a Stem Cells Int (2016)

HectH9 hijacks glucose metabolism to fuel tumor growth

per Lee, Hong-Jen, He, Jiabei, Chan, Chia-Hsin
Publicat a Mol Cell Oncol (2019)

Novel ARF/p53-independent senescence pathways in cancer repression

per Chan, Chia-Hsin, Gao, Yuan, Moten, Asad, Lin, Hui-Kuan
Publicat 2011

Novel roles of Skp2 E3 ligase in cellular senescence, cancer progression, and metastasis

per Wang, Guocan, Chan, Chia-Hsin, Gao, Yuan, Lin, Hui-Kuan
Publicat 2012

Two-faced activity of RNF8: What “twists” it from a genome guardian to a cancer facilitator?

per Lee, Hong-Jen, Ruan, Diane, He, Jiabei, Chan, Chia-Hsin
Publicat a Mol Cell Oncol (2016)

Skp2: A dream target in the coming age of cancer therapy

per Chan, Chia-Hsin, Morrow, John Kenneth, Zhang, Shuxing, Lin, Hui-Kuan
Publicat 2014

Regulation of Skp2 Expression and Activity and Its Role in Cancer Progression

per Chan, Chia-Hsin, Lee, Szu-Wei, Wang, Jing, Lin, Hui-Kuan
Publicat a ScientificWorldJournal (2010)

The ubiquitin ligase RNF8 regulates Rho GTPases and promotes cytoskeletal changes and motility in triple‐negative breast cancer cells

per Pereira De Carvalho, Bruno, Chern, Yi‐Jye, He, Jiabei, Chan, Chia‐Hsin
Publicat a FEBS Lett (2020)

Inhibition of USP2 eliminates cancer stem cells and enhances TNBC responsiveness to chemotherapy

per He, Jiabei, Lee, Hong-Jen, Saha, Suchandrima, Ruan, Diane, Guo, Hua, Chan, Chia-Hsin
Publicat a Cell Death Dis (2019)

Posttranslational regulation of Akt in human cancer

per Chan, Chia-Hsin, Jo, Ukhyun, Kohrman, Abraham, Rezaeian, Abdol Hossein, Chou, Ping-Chieh, Logothetis, Christopher, Lin, Hui-Kuan
Publicat 2014

Skp2 deficiency restricts the progression and stem cell features of castration-resistant prostate cancer by destabilizing Twist

per Ruan, Diane, He, Jiabei, Li, Chien-Feng, Lee, Hong-Jen, Liu, Jingxuan, Lin, Hui-Kuan, Chan, Chia-Hsin
Publicat a Oncogene (2017)

The Oxygen-Generating Calcium Peroxide-Modified Magnetic Nanoparticles Attenuate Hypoxia-Induced Chemoresistance in Triple-Negative Breast Cancer

per Cheng, Fong-Yu, Chan, Chia-Hsin, Wang, Bour-Jr, Yeh, Ya-Ling, Wang, Ying-Jan, Chiu, Hui-Wen
Publicat a Cancers (Basel) (2021)

The DNA damage transducer RNF8 facilitates cancer chemoresistance and progression through Twist activation

per Lee, Hong-Jen, Li, Chien-Feng, Ruan, Diane, Powers, Scott, Thompson, Patricia A, Frohman, Michael A., Chan, Chia-Hsin
Publicat a Mol Cell (2016)

UTX and MLL4 Coordinately Regulate Transcriptional Programs for Cell Proliferation and Invasiveness in Breast Cancer Cells

per Kim, Jae-Hwan, Sharma, Amrish, Dhar, Shilpa S., Lee, Sung-Hun, Gu, Bingnan, Chan, Chia-Hsin, Lin, Hui-Kuan, Lee, Min Gyu
Publicat 2014

Non-proteolytic ubiquitination of Hexokinase 2 by HectH9 controls tumor metabolism and cancer stem cell expansion

per Lee, Hong-Jen, Li, Chien-Feng, Ruan, Diane, He, Jiabei, Montal, Emily D., Lorenz, Sonja, Girnun, Geoffrey D., Chan, Chia-Hsin
Publicat a Nat Commun (2019)

MIG‐6 is essential for promoting glucose metabolic reprogramming and tumor growth in triple‐negative breast cancer

per He, Jiabei, Li, Chien‐Feng, Lee, Hong‐Jen, Shin, Dong‐Hui, Chern, Yi‐Jye, Pereira De Carvalho, Bruno, Chan, Chia‐Hsin
Publicat a EMBO Rep (2021)

The E3 Ligase TRAF6 Regulates Akt Ubiquitination and Activation

per Yang, Wei-Lei, Wang, Jing, Chan, Chia-Hsin, Lee, Szu-Wei, Campos, Alejandro D., Hur, Lana, Grabiner, Brian, Lin, Xin, Darnay, Bryant G., Lin, Hui-Kuan
Publicat 2009

Loss of TGF-β Adaptor β2SP Activates Notch Signaling and SOX9 Expression in Esophageal Adenocarcinoma

per Song, Shumei, Maru, Dipen M., Ajani, Jaffer A., Chan, Chia-Hsin, Honjo, Soichiro, Lin, Hui-Kuan, Correa, Arlene, Hofstetter, Wayne L., Davila, Marta, Stroehlein, John, Mishra, Lopa
Publicat 2013

JARID1D is a suppressor and prognostic marker of prostate cancer invasion and metastasis

per Li, Na, Dhar, Shilpa S., Chen, Tsai-Yu, Kan, Pu-Yeh, Wei, Yongkun, Kim, Jae-Hwan, Chan, Chia-Hsin, Lin, Hui-Kuan, Hung, Mien-Chie, Lee, Min Gyu
Publicat a Cancer Res (2016)