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The E3 Ligase TRAF6 Regulates Akt Ubiquitination and Activation
Akt signaling plays a central role in many biological functions, such as cell proliferation and apoptosis. Since Akt resides primarily in the cytosol, it is not known how these signaling molecules are recruited to the plasma membrane and subsequently activated by growth factor stimuli. Here, we foun...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3008763/ https://ncbi.nlm.nih.gov/pubmed/19713527 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1175065 |
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