The E3 Ligase TRAF6 Regulates Akt Ubiquitination and Activation

Akt signaling plays a central role in many biological functions, such as cell proliferation and apoptosis. Since Akt resides primarily in the cytosol, it is not known how these signaling molecules are recruited to the plasma membrane and subsequently activated by growth factor stimuli. Here, we foun...

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Bibliografiske detaljer
Main Authors: Yang, Wei-Lei, Wang, Jing, Chan, Chia-Hsin, Lee, Szu-Wei, Campos, Alejandro D., Hur, Lana, Grabiner, Brian, Lin, Xin, Darnay, Bryant G., Lin, Hui-Kuan
Format: Artigo
Sprog:Inglês
Udgivet: 2009
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3008763/
https://ncbi.nlm.nih.gov/pubmed/19713527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1175065
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