Caricamento...
The DNA damage transducer RNF8 facilitates cancer chemoresistance and progression through Twist activation
Twist has been shown to cause treatment failure, cancer progression and cancer-related death. However, strategies that directly target Twist are not yet conceivable. Here we revealed K63-linked ubiquitination is a crucial regulatory mechanism for Twist activation. Through an E3 ligase screen and bio...
Salvato in:
| Pubblicato in: | Mol Cell |
|---|---|
| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2016
|
| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5026628/ https://ncbi.nlm.nih.gov/pubmed/27618486 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2016.08.009 |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !
|