Loss of TGF-β Adaptor β2SP Activates Notch Signaling and SOX9 Expression in Esophageal Adenocarcinoma

TGF-β and Notch signaling pathways play important roles in regulating self-renewal of stem cells and gastrointestinal carcinogenesis. Loss of TGF-β signaling components activates Notch signaling in esophageal adenocarcinoma, but the basis for this effect has been unclear. Here we report that loss of...

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Detalhes bibliográficos
Main Authors: Song, Shumei, Maru, Dipen M., Ajani, Jaffer A., Chan, Chia-Hsin, Honjo, Soichiro, Lin, Hui-Kuan, Correa, Arlene, Hofstetter, Wayne L., Davila, Marta, Stroehlein, John, Mishra, Lopa
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3745222/
https://ncbi.nlm.nih.gov/pubmed/23536563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-1962
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