Hippo coactivator YAP1 upregulates SOX9 and endows stem-like properties to esophageal cancer cells

Cancer stem cells are proposed to initiate and maintain tumor growth. Deregulation of normal stem cell signaling may lead to the generation of cancer stem cells (CSCs); however, the molecular determinants of this process remain poorly understood. Here we show that the transcriptional co-activator YA...

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Detalhes bibliográficos
Main Authors: Song, Shumei, Ajani, Jaffer A., Honjo, Soichiro, Maru, Dipen M, Chen, Qiongrong, Scott, Ailing W, Heallen, Todd R., Xiao, Lianchun, Hofstetter, Wayne L., Weston, Brian, Lee, Jeffrey H., Wadhwa, Roopma, Sudo, Kazuki, Stroehlein, John R, Martin, James F., Hung, Mien-Chie, Johnson, Randy L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136429/
https://ncbi.nlm.nih.gov/pubmed/24906622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-3569
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