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Metformin sensitizes chemotherapy by targeting cancer stem cells and the mTOR pathway in esophageal cancer

Our clinical study indicates esophageal adenocarcinoma patients on metformin had a better treatment response than those without metformin. However, the effects of metformin and the mechanisms of its action in esophageal cancer (EC) are unclear. EC cell lines were used to assess the effects of metfor...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: HONJO, SOICHIRO, AJANI, JAFFER A., SCOTT, AILING W., CHEN, QIONGRONG, SKINNER, HEATH D., STROEHLEIN, JOHN, JOHNSON, RANDY L., SONG, SHUMEI
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: D.A. Spandidos 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4091970/
https://ncbi.nlm.nih.gov/pubmed/24859412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2014.2450
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