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Metformin sensitizes chemotherapy by targeting cancer stem cells and the mTOR pathway in esophageal cancer

Our clinical study indicates esophageal adenocarcinoma patients on metformin had a better treatment response than those without metformin. However, the effects of metformin and the mechanisms of its action in esophageal cancer (EC) are unclear. EC cell lines were used to assess the effects of metfor...

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Detalhes bibliográficos
Main Authors: HONJO, SOICHIRO, AJANI, JAFFER A., SCOTT, AILING W., CHEN, QIONGRONG, SKINNER, HEATH D., STROEHLEIN, JOHN, JOHNSON, RANDY L., SONG, SHUMEI
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4091970/
https://ncbi.nlm.nih.gov/pubmed/24859412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2014.2450
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