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Targeting Hippo coactivator YAP1 through BET bromodomain inhibition in esophageal adenocarcinoma
Hippo/YAP1 signaling is a major regulator of organ size, cancer stemness, and aggressive phenotype. Thus, targeting YAP1 may provide a novel therapeutic strategy for tumors with high YAP1 expression in esophageal cancer (EC). Chromatin immunoprecipitation (ChiP) and quantitative ChiP‐PCR were used t...
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| 出版年: | Mol Oncol |
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| 主要な著者: | , , , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
John Wiley and Sons Inc.
2020
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7266288/ https://ncbi.nlm.nih.gov/pubmed/32175692 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12667 |
| タグ: |
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