High-salt intake enhances superoxide activity in eNOS knockout mice leading to the development of salt sensitivity

Por Kopkan, Libor, Hess, Arthur, Husková, Zuzana, Červenka, Luděk, Navar, L. Gabriel, Majid, Dewan S. A.
Publicado em 2010

Conditional knockout of collecting duct bradykinin B(2) receptors exacerbates angiotensin II-induced hypertension during high salt intake

Por Kopkan, Libor, Husková, Zuzana, Jíchová, Šárka, Červenková, Lenka, Červenka, Luděk, Saifudeen, Zubaida, El-Dahr, Samir S.
Publicado no Clin Exp Hypertens (2015)

Interlobular arteries from two-kidney, one-clip Goldblatt hypertensive rats exhibit impaired vasodilator response to epoxyeicosatrienoic acids

Por Sporková, Alexandra, Reddy, N. Rami, Falck, John R., Imig, John D., Kopkan, Libor, Sadowski, Janusz, Červenka, Luděk
Publicado no Am J Med Sci (2016)

Antihypertensive action of soluble epoxide hydrolase inhibition in Ren-2 transgenic rats is mediated by suppression of the intrarenal renin-angiotensin system

Por Varcabová, Šárka, Husková, Zuzana, Kramer, Herbert J., Hwang, Sung Hee, Hammock, Bruce D., Imig, John D., Kitada, Kento, Červenka, Luděk
Publicado em 2013

Role of cytochrome P-450 metabolites in the regulation of renal function and blood pressure in 2-kidney 1-clip hypertensive rats

Por Sporková, Alexandra, Kopkan, Libor, Varcabová, Šárka, Husková, Zuzana, Hwang, Sung Hee, Hammock, Bruce D., Imig, John D., Kramer, Herbert J., Červenka, Luděk
Publicado em 2011

Inhibition of soluble epoxide hydrolase does not improve the course of congestive heart failure and the development of renal dysfunction in rats with volume overload induced by aor...

Por Červenka, Luděk, Melenovský, Vojtěch, Husková, Zuzana, Sporková, Alexandra, Bürgelová, Marcela, Škaroupková, Petra, Hwang, Sung Hee, Hammock, Bruce D., Imig, John D., Sadowski, Janusz
Publicado no Physiol Res (2015)

Proteomic and transcriptomic analysis of heart failure due to volume overload in a rat aorto-caval fistula model provides support for new potential therapeutic targets - monoamine...

Por Petrak, Jiri, Pospisilova, Jana, Sedinova, Miroslava, Jedelsky, Petr, Lorkova, Lucie, Vit, Ondrej, Kolar, Michal, Strnad, Hynek, Benes, Jan, Sedmera, David, Cervenka, Ludek, Melenovsky, Vojtech
Publicado em 2011

Effect of angiotensin-converting enzyme blockade alone or combined with blockade of soluble epoxide hydrolase on the course of congestive heart failure and occurrence of renal dysf...

Por Kala, Petr, Sedláková, Lenka, Škaroupková, Petra, Kopkan, Libor, Vaňourková, Zdenka, Táborský, Miloš, Nishiyama, Akira, Hwang, Sung Hee, Hammock, Bruce D., Sadowski, Janusz, Melenovský, Vojtěch, Červenka, Luděk
Publicado no Physiol Res (2018)

Renal mechanisms contributing to the antihypertensive action of soluble epoxide hydrolase inhibition in Ren-2 transgenic rats with inducible hypertension

Por Honetschlägerová, Zuzana, Husková, Zuzana, Vaňourková, Zdeňka, Sporková, Alexandra, Kramer, Herbert J, Hwang, Sung Hee, Tsai, Hsing-Ju, Hammock, Bruce D, Imig, John D, Červenka, Luděk, Kopkan, Libor
Publicado em 2011

Effects of Angiotensin II AT(1)–Receptor Blockade on High Fat Diet–Induced Vascular Oxidative Stress and Endothelial Dysfunction in Dahl Salt-Sensitive Rats

Por Kosaka, Shinji, Pelisch, Nicolas, Rahman, Matlubur, Nakano, Daisuke, Hitomi, Hirofumi, Kobori, Hiroyuki, Fukuoka, Noriyasu, Kobara, Hideki, Mori, Hirohito, Masaki, Tsutomu, Cervenka, Ludek, Matsumura, Yasuo, Houchi, Hitoshi, Nishiyama, Akira
Publicado em 2013

Isovolumic loading of the failing heart by intraventricular placement of a spring expander attenuates cardiac atrophy after heterotopic heart transplantation

Por Pokorný, Martin, Mrázová, Iveta, Šochman, Jan, Melenovský, Vojtěch, Malý, Jiří, Pirk, Jan, Červenková, Lenka, Sadowski, Janusz, Čermák, Zdeněk, Volenec, Karel, Vacková, Šárka, Maxová, Hana, Červenka, Luděk, Netuka, Ivan
Publicado no Biosci Rep (2018)

Different mechanisms of acute versus long term antihypertensive effects of soluble epoxide hydrolase inhibition: studies in Cyp1a1-Ren-2 transgenic rats

Por Sporková, Alexandra, Jíchová, Šárka, Husková, Zuzana, Kopkan, Libor, Nishiyama, Akira, Hwang, Sung Hee, Hammock, Bruce D., Imig, John D., Kompanowska-Jezierska, Elzbieta, Sadowski, Janusz, Kramer, Herbert J., Červenka, Luděk
Publicado no Clin Exp Pharmacol Physiol (2014)

20-Hydroxyeicosatetraenoic acid antagonist attenuates the development of malignant hypertension and reverses it once established: a study in Cyp1a1-Ren-2 transgenic rats

Por Sedláková, Lenka, Kikerlová, Soňa, Husková, Zuzana, Červenková, Lenka, Chábová, Věra Čertíková, Zicha, Josef, Falck, John R., Imig, John D., Kompanowska-Jezierska, Elzbieta, Sadowski, Janusz, Krátký, Vojtěch, Červenka, Luděk, Kopkan, Libor
Publicado no Biosci Rep (2018)

Intrarenal CYP-450 metabolites of arachidonic acid in the regulation of the nonclipped kidney function in two-kidney, one-clip Goldblatt hypertensive rats

Por Walkowska, Agnieszka, Thumová, Monika, Škaroupková, Petra, Husková, Zuzana, Vaňourková, Zdenka, Chábová, Věra Čertíková, Tesař, Vladimír, Kramer, Herbert J., Falck, John R., Imig, John D., Kompanowska-Jezierska, Elzbieta, Sadowski, Janusz, Červenka, Luděk
Publicado em 2010

Inhibition of soluble epoxide hydrolase by cis-4-[4-(3-adamantan-1-yl-ureido)cyclohexyl-oxy]benzoic acid exhibits antihypertensive and cardioprotective actions in transgenic rats w...

Por Neckár̆, Jan, Kopkan, Libor, Husková, Zuzana, Kolár̆, Frantis̆ek, Papous̆ek, Frantis̆ek, Kramer, Herbert J., Hwang, Sung Hee, Hammock, Bruce D., Imig, John D., Malý, Jir̆í, Netuka, Ivan, Os̆t’ádal, Bohuslav, C̆ervenka, Ludĕk
Publicado em 2012

Inhibition of soluble epoxide hydrolase improves the impaired pressure–natriuresis relationship and attenuates the development of hypertension and hypertension-associated end-organ...

Por Honetschlägerová, Zuzana, Sporková, Alexandra, Kopkan, Libor, Husková, Zuzana, Hwang, Sung H., Hammock, Bruce D., Imig, John D., Kramer, Herbert J., Kujal, Petr, Vernerová, Zdenka, Chábová, Věra Č., Tesař, Vladimír, Červenka, Luděk
Publicado em 2011

Epoxyeicosatrienoic acid analog attenuates the development of malignant hypertension, but does not reverse it once established: a study in Cyp1a1-Ren-2 transgenic rats

Por Jíchová, Šárka, Kopkan, Libor, Husková, Zuzana, Doleželová, Šárka, Neckář, Jan, Kujal, Petr, Vernerová, Zdenka, Kramer, Herbert J., Sadowski, Janusz, Kompanowska-Jezierska, Elzbieta, Reddy, Rami N., Falck, John R., Imig, John D., Červenka, Luděk
Publicado no J Hypertens (2016)

Combined inhibition of 20-hydroxyeicosatetraenoic acid formation and of epoxyeicosatrienoic acids degradation attenuates hypertension and hypertension-induced end-organ damage in R...

Por Čertíková Chábová, Věra, Walkowska, Agnieszka, Kompanowska-Jezierska, Elzbieta, Sadowski, Janusz, Kujal, Petr, Vernerová, Zdena, Vaňourková, Zdenka, Kopkan, Libor, Kramer, Herbert J., Falck, John R., Imig, John D., Hammock, Bruce D., Vaněčková, Ivana, Červenka, Luděk
Publicado em 2010

Antihypertensive and renoprotective actions of soluble epoxide hydrolase inhibition in ANG II-dependent malignant hypertension are abolished by pretreatment with L-NAME

Por Honetschlägerová, Zuzana, Kitada, Kento, Husková, Zuzana, Sporková, Alexandra, Kopkan, Libor, Bürgelová, Marcela, Varcabová, Šárka, Nishiyama, Akira, Hwang, Sung Hee, Hammock, Bruce D., Imig, John D., Kramer, Herbert J., Kujal, Petr, Vernerová, Zdenka, Červenka, Luděk
Publicado em 2013

Soluble epoxide hydrolase inhibition exhibits antihypertensive actions independently of nitric oxide in mice with renovascular hypertension

Por Kopkan, Libor, Husková, Zuzana, Sporková, Alexandra, Varcabová, Šárka, Honetschlägerová, Zuzana, Hwang, Sung Hee, Tsai, Hsing-Ju, Hammock, Bruce D., Imig, John D., Kramer, Herbert J., Bürgelová, Marcela, Vojtíšková, Alžběta, Kujal, Petr, Vernerová, Zdenka, Červenka, Luděk
Publicado em 2012