Effect of angiotensin-converting enzyme blockade alone or combined with blockade of soluble epoxide hydrolase on the course of congestive heart failure and occurrence of renal dysfunction in Ren-2 transgenic hypertensive rats with aorto-caval fistula

Our recent study showed that increasing epoxyeicosatrienoic acids (EETs) in kidney by blocking soluble epoxide hydrolase (sEH), an enzyme responsible for EETs degradation, retarded the development of renal dysfunction and progression of aorto-caval (ACF)-induced congestive heart failure (CHF) in Ren...

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Detalhes bibliográficos
Publicado no:Physiol Res
Main Authors: Kala, Petr, Sedláková, Lenka, Škaroupková, Petra, Kopkan, Libor, Vaňourková, Zdenka, Táborský, Miloš, Nishiyama, Akira, Hwang, Sung Hee, Hammock, Bruce D., Sadowski, Janusz, Melenovský, Vojtěch, Červenka, Luděk
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6056335/
https://ncbi.nlm.nih.gov/pubmed/29527914
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