Pharmacological Blockade of Soluble Epoxide Hydrolase Attenuates the Progression of Congestive Heart Failure Combined With Chronic Kidney Disease: Insights From Studies With Fawn-Hooded Hypertensive Rats

An association between congestive heart failure (CHF) and chronic kidney disease (CKD) results in extremely poor patient survival rates. Previous studies have shown that increasing kidney epoxyeicosatrienoic acids (EETs) by blocking soluble epoxide hydrolase (sEH), an enzyme responsible for EETs deg...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Vacková, Šárka, Kopkan, Libor, Kikerlová, Soňa, Husková, Zuzana, Sadowski, Janusz, Kompanowska-Jezierska, Elzbieta, Hammock, Bruce D., Imig, John D., Táborský, Miloš, Melenovský, Vojtěch, Červenka, Luděk
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6351500/
https://ncbi.nlm.nih.gov/pubmed/30728778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00018
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