Antihypertensive and renoprotective actions of soluble epoxide hydrolase inhibition in ANG II-dependent malignant hypertension are abolished by pretreatment with L-NAME

OBJECTIVE: The present study was performed to investigate in a model of malignant hypertension if the antihypertensive actions of soluble epoxide hydrolase (sEH) inhibition are nitric oxide (NO)-dependent. METHODS: ANG II-dependent malignant hypertension was induced through dietary administration fo...

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Detalhes bibliográficos
Main Authors: Honetschlägerová, Zuzana, Kitada, Kento, Husková, Zuzana, Sporková, Alexandra, Kopkan, Libor, Bürgelová, Marcela, Varcabová, Šárka, Nishiyama, Akira, Hwang, Sung Hee, Hammock, Bruce D., Imig, John D., Kramer, Herbert J., Kujal, Petr, Vernerová, Zdenka, Červenka, Luděk
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3773167/
https://ncbi.nlm.nih.gov/pubmed/23307303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/HJH.0b013e32835b50aa
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