Development of Diaminoquinazoline Histone Lysine Methyltransferase Inhibitors as Potent Blood-stage Anti-Malarial Compounds

ανά Sundriyal, Sandeep, Malmquist, Nicholas A., Caron, Joachim, Blundell, Scott, Liu, Feng, Chen, Xin, Srimongkolpithak, Nitipol, Jin, Jian, Charman, Susan A., Scherf, Artur, Fuchter, Matthew J.
Έκδοση 2014

Dual EZH2 and EHMT2 histone methyltransferase inhibition increases biological efficacy in breast cancer cells

ανά Curry, Edward, Green, Ian, Chapman-Rothe, Nadine, Shamsaei, Elham, Kandil, Sarah, Cherblanc, Fanny L, Payne, Luke, Bell, Emma, Ganesh, Thota, Srimongkolpithak, Nitipol, Caron, Joachim, Li, Fengling, Uren, Anthony G., Snyder, James P., Vedadi, Masoud, Fuchter, Matthew J., Brown, Robert
Τόπος έκδοσης Clin Epigenetics (2015)

Histone Methyltransferase Inhibitors Are Orally Bioavailable, Fast-Acting Molecules with Activity against Different Species Causing Malaria in Humans

ανά Malmquist, Nicholas A., Sundriyal, Sandeep, Caron, Joachim, Chen, Patty, Witkowski, Benoit, Menard, Didier, Suwanarusk, Rossarin, Renia, Laurent, Nosten, Francois, Jiménez-Díaz, María Belén, Angulo-Barturen, Iñigo, Martínez, María Santos, Ferrer, Santiago, Sanz, Laura M., Gamo, Francisco-Javier, Wittlin, Sergio, Duffy, Sandra, Avery, Vicky M., Ruecker, Andrea, Delves, Michael J., Sinden, Robert E., Fuchter, Matthew J., Scherf, Artur
Τόπος έκδοσης Antimicrob Agents Chemother (2015)