Fusion transcripts: Unexploited vulnerabilities in cancer?

di Neckles, Carla, Sundara Rajan, Soumya, Caplen, Natasha J.
Pubblicato in Wiley Interdiscip Rev RNA (2019)

Genomic instability and mouse microRNAs

di Huppi, Konrad, Pitt, Jason, Wahlberg, Brady, Caplen, Natasha J.
Pubblicazione 2011

The 8q24 Gene Desert: An Oasis of Non-Coding Transcriptional Activity

di Huppi, Konrad, Pitt, Jason J., Wahlberg, Brady M., Caplen, Natasha J.
Pubblicazione 2012

Specific inhibition of gene expression by small double-stranded RNAs in invertebrate and vertebrate systems

di Caplen, Natasha J., Parrish, Susan, Imani, Farhad, Fire, Andrew, Morgan, Richard A.
Pubblicazione 2001

Implication of Checkpoint Kinase-dependent Up-regulation of Ribonucleotide Reductase R2 in DNA Damage Response

di Zhang, Yong-Wei, Jones, Tamara L., Martin, Scott E., Caplen, Natasha J., Pommier, Yves
Pubblicazione 2009

p53-dependent Induction of PVT1 and miR-1204

di Barsotti, Anthony M., Beckerman, Rachel, Laptenko, Oleg, Huppi, Konrad, Caplen, Natasha J., Prives, Carol
Pubblicazione 2012

Identification of WEE1 as a potential molecular target in cancer cells by RNAi screening of the human tyrosine kinome

di Murrow, Lyndsay M., Garimella, Sireesha V., Jones, Tamara L., Caplen, Natasha J., Lipkowitz, Stanley
Pubblicazione 2009

Efficient Delivery of RNAi Effectors via In Vitro-Packaged SV40 Pseudovirions

di KIMCHI-SARFATY, CHAVA, BRITTAIN, SCOTT, GARFIELD, SUSAN, CAPLEN, NATASHA J., TANG, QINGQUAN, GOTTESMAN, MICHAEL M.
Pubblicazione 2005

Identification of the receptor tyrosine kinase AXL in breast cancer as a target for the human miR-34a microRNA

di Mackiewicz, Mark, Huppi, Konrad, Pitt, Jason J., Dorsey, Tiffany H., Ambs, Stefan, Caplen, Natasha J.
Pubblicazione 2011

Cancer biology functional genomics: From small RNAs to big dreams

di Sundara Rajan, Soumya, Ludwig, Katelyn R., Hall, Katherine L., Jones, Tamara L., Caplen, Natasha J.
Pubblicato in Mol Carcinog (2020)

Pvt1-encoded microRNAs in oncogenesis

di Beck-Engeser, Gabriele B, Lum, Amy M, Huppi, Konrad, Caplen, Natasha J, Wang, Bruce B, Wabl, Matthias
Pubblicazione 2008

EWS‐FLI1 reprograms the metabolism of Ewing sarcoma cells via positive regulation of glutamine import and serine‐glycine biosynthesis

di Sen, Nirmalya, Cross, Allison M., Lorenzi, Philip L., Khan, Javed, Gryder, Berkley E., Kim, Suntae, Caplen, Natasha J.
Pubblicato in Mol Carcinog (2018)

MicroRNAs and Genomic Instability

di Huppi, Konrad, Volfovsky, Natalia, Mackiewicz, Mark, Runfola, Timothy, Jones, Tamara L., Martin, Scott E., Stephens, Robert, Caplen, Natasha J.
Pubblicazione 2006

SpliceCenter: A suite of web-based bioinformatic applications for evaluating the impact of alternative splicing on RT-PCR, RNAi, microarray, and peptide-based studies

di Liu Hongfang, Cleland James A, Kahn Ari B, Caplen Natasha J, Zeeberg Barry R, Ryan Michael C, Weinstein John N
Pubblicazione 2008-07-01

SpliceCenter: A suite of web-based bioinformatic applications for evaluating the impact of alternative splicing on RT-PCR, RNAi, microarray, and peptide-based studies

di Ryan, Michael C, Zeeberg, Barry R, Caplen, Natasha J, Cleland, James A, Kahn, Ari B, Liu, Hongfang, Weinstein, John N
Pubblicazione 2008

Inhibition of PLK1 in glioblastoma multiforme induces mitotic catastrophe and enhances radiosensitization

di Tandle, Anita T., Kramp, Tamalee, Kil, Whoon J, Halthore, Aditya, Gehlhaus, Kristen, Shankavaram, Uma, Tofilon, Philip J., Caplen, Natasha J., Camphausen, Kevin
Pubblicazione 2013

Allele-specific silencing of the dominant disease allele in sialuria by RNA interference

di Klootwijk, Riko D., Savelkoul, Paul J. M., Ciccone, Carla, Manoli, Irini, Caplen, Natasha J., Krasnewich, Donna M., Gahl, William A., Huizing, Marjan
Pubblicazione 2008

Targeting MPS1 Enhances Radiosensitization of Human Glioblastoma by Modulating DNA Repair Proteins

di Maachani, Uday B., Kramp, Tamalee, Hanson, Ryan, Zhao, Shuping, Celiku, Orieta, Shankavaram, Uma, Colombo, Riccardo, Caplen, Natasha J., Camphausen, Kevin, Tandle, Anita
Pubblicato in Mol Cancer Res (2015)

Identification of novel molecular regulators of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in breast cancer cells by RNAi screening

di Garimella, Sireesha V, Gehlhaus, Kristie, Dine, Jennifer L, Pitt, Jason J, Grandin, Magdalena, Chakka, Sirisha, Nau, Marion M, Caplen, Natasha J, Lipkowitz, Stanley
Pubblicazione 2014

HNRNPH1-dependent splicing of a fusion oncogene reveals a targetable RNA G-quadruplex interaction

di Neckles, Carla, Boer, Robert E., Aboreden, Nicholas, Cross, Allison M., Walker, Robert L., Kim, Bong-Hyun, Kim, Suntae, Schneekloth, John S., Caplen, Natasha J.
Pubblicato in RNA (2019)