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p53-dependent Induction of PVT1 and miR-1204

p53 is a tumor suppressor protein that acts as a transcription factor to regulate (either positively or negatively) a plethora of downstream target genes. Although its ability to induce protein coding genes is well documented, recent studies have implicated p53 in the regulation of non-coding RNAs,...

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Autori principali: Barsotti, Anthony M., Beckerman, Rachel, Laptenko, Oleg, Huppi, Konrad, Caplen, Natasha J., Prives, Carol
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3268411/
https://ncbi.nlm.nih.gov/pubmed/22110125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.322875
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