Fusion transcripts: Unexploited vulnerabilities in cancer?

Por Neckles, Carla, Sundara Rajan, Soumya, Caplen, Natasha J.
Publicado no Wiley Interdiscip Rev RNA (2019)

Genomic instability and mouse microRNAs

Por Huppi, Konrad, Pitt, Jason, Wahlberg, Brady, Caplen, Natasha J.
Publicado em 2011

The 8q24 Gene Desert: An Oasis of Non-Coding Transcriptional Activity

Por Huppi, Konrad, Pitt, Jason J., Wahlberg, Brady M., Caplen, Natasha J.
Publicado em 2012

Specific inhibition of gene expression by small double-stranded RNAs in invertebrate and vertebrate systems

Por Caplen, Natasha J., Parrish, Susan, Imani, Farhad, Fire, Andrew, Morgan, Richard A.
Publicado em 2001

Implication of Checkpoint Kinase-dependent Up-regulation of Ribonucleotide Reductase R2 in DNA Damage Response

Por Zhang, Yong-Wei, Jones, Tamara L., Martin, Scott E., Caplen, Natasha J., Pommier, Yves
Publicado em 2009

p53-dependent Induction of PVT1 and miR-1204

Por Barsotti, Anthony M., Beckerman, Rachel, Laptenko, Oleg, Huppi, Konrad, Caplen, Natasha J., Prives, Carol
Publicado em 2012

Identification of WEE1 as a potential molecular target in cancer cells by RNAi screening of the human tyrosine kinome

Por Murrow, Lyndsay M., Garimella, Sireesha V., Jones, Tamara L., Caplen, Natasha J., Lipkowitz, Stanley
Publicado em 2009

Efficient Delivery of RNAi Effectors via In Vitro-Packaged SV40 Pseudovirions

Por KIMCHI-SARFATY, CHAVA, BRITTAIN, SCOTT, GARFIELD, SUSAN, CAPLEN, NATASHA J., TANG, QINGQUAN, GOTTESMAN, MICHAEL M.
Publicado em 2005

Identification of the receptor tyrosine kinase AXL in breast cancer as a target for the human miR-34a microRNA

Por Mackiewicz, Mark, Huppi, Konrad, Pitt, Jason J., Dorsey, Tiffany H., Ambs, Stefan, Caplen, Natasha J.
Publicado em 2011

Cancer biology functional genomics: From small RNAs to big dreams

Por Sundara Rajan, Soumya, Ludwig, Katelyn R., Hall, Katherine L., Jones, Tamara L., Caplen, Natasha J.
Publicado no Mol Carcinog (2020)

Pvt1-encoded microRNAs in oncogenesis

Por Beck-Engeser, Gabriele B, Lum, Amy M, Huppi, Konrad, Caplen, Natasha J, Wang, Bruce B, Wabl, Matthias
Publicado em 2008

EWS‐FLI1 reprograms the metabolism of Ewing sarcoma cells via positive regulation of glutamine import and serine‐glycine biosynthesis

Por Sen, Nirmalya, Cross, Allison M., Lorenzi, Philip L., Khan, Javed, Gryder, Berkley E., Kim, Suntae, Caplen, Natasha J.
Publicado no Mol Carcinog (2018)

MicroRNAs and Genomic Instability

Por Huppi, Konrad, Volfovsky, Natalia, Mackiewicz, Mark, Runfola, Timothy, Jones, Tamara L., Martin, Scott E., Stephens, Robert, Caplen, Natasha J.
Publicado em 2006

SpliceCenter: A suite of web-based bioinformatic applications for evaluating the impact of alternative splicing on RT-PCR, RNAi, microarray, and peptide-based studies

Por Liu Hongfang, Cleland James A, Kahn Ari B, Caplen Natasha J, Zeeberg Barry R, Ryan Michael C, Weinstein John N
Publicado em 2008-07-01

SpliceCenter: A suite of web-based bioinformatic applications for evaluating the impact of alternative splicing on RT-PCR, RNAi, microarray, and peptide-based studies

Por Ryan, Michael C, Zeeberg, Barry R, Caplen, Natasha J, Cleland, James A, Kahn, Ari B, Liu, Hongfang, Weinstein, John N
Publicado em 2008

Inhibition of PLK1 in glioblastoma multiforme induces mitotic catastrophe and enhances radiosensitization

Por Tandle, Anita T., Kramp, Tamalee, Kil, Whoon J, Halthore, Aditya, Gehlhaus, Kristen, Shankavaram, Uma, Tofilon, Philip J., Caplen, Natasha J., Camphausen, Kevin
Publicado em 2013

Allele-specific silencing of the dominant disease allele in sialuria by RNA interference

Por Klootwijk, Riko D., Savelkoul, Paul J. M., Ciccone, Carla, Manoli, Irini, Caplen, Natasha J., Krasnewich, Donna M., Gahl, William A., Huizing, Marjan
Publicado em 2008

Targeting MPS1 Enhances Radiosensitization of Human Glioblastoma by Modulating DNA Repair Proteins

Por Maachani, Uday B., Kramp, Tamalee, Hanson, Ryan, Zhao, Shuping, Celiku, Orieta, Shankavaram, Uma, Colombo, Riccardo, Caplen, Natasha J., Camphausen, Kevin, Tandle, Anita
Publicado no Mol Cancer Res (2015)

Identification of novel molecular regulators of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in breast cancer cells by RNAi screening

Por Garimella, Sireesha V, Gehlhaus, Kristie, Dine, Jennifer L, Pitt, Jason J, Grandin, Magdalena, Chakka, Sirisha, Nau, Marion M, Caplen, Natasha J, Lipkowitz, Stanley
Publicado em 2014

HNRNPH1-dependent splicing of a fusion oncogene reveals a targetable RNA G-quadruplex interaction

Por Neckles, Carla, Boer, Robert E., Aboreden, Nicholas, Cross, Allison M., Walker, Robert L., Kim, Bong-Hyun, Kim, Suntae, Schneekloth, John S., Caplen, Natasha J.
Publicado no RNA (2019)