SpliceCenter: A suite of web-based bioinformatic applications for evaluating the impact of alternative splicing on RT-PCR, RNAi, microarray, and peptide-based studies

BACKGROUND: Over 60% of protein-coding genes in vertebrates express mRNAs that undergo alternative splicing. The resulting collection of transcript isoforms poses significant challenges for contemporary biological assays. For example, RT-PCR validation of gene expression microarray results may be un...

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Autores principales: Ryan, Michael C, Zeeberg, Barry R, Caplen, Natasha J, Cleland, James A, Kahn, Ari B, Liu, Hongfang, Weinstein, John N
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2008
Materias:
Database
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2491637/
https://ncbi.nlm.nih.gov/pubmed/18638396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-9-313
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