Targeting MPS1 Enhances Radiosensitization of Human Glioblastoma by Modulating DNA Repair Proteins

To ensure faithful chromosome segregation, cells use the spindle assembly checkpoint (SAC), which can be activated in aneuploid cancer cells. Targeting the components of SAC machinery required for the growth of aneuploid cells may offer a cancer cell specific therapeutic approach. In this study, the...

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發表在:Mol Cancer Res
Main Authors: Maachani, Uday B., Kramp, Tamalee, Hanson, Ryan, Zhao, Shuping, Celiku, Orieta, Shankavaram, Uma, Colombo, Riccardo, Caplen, Natasha J., Camphausen, Kevin, Tandle, Anita
格式: Artigo
語言:Inglês
出版: 2015
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4433451/
https://ncbi.nlm.nih.gov/pubmed/25722303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-14-0462-T
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