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RT-18 TARGETING MPS1 ENHANCES RADIOSENSITIZATION OF HUMAN GLIOBLASTOMA BY MODULATING DNA REPAIR PROTEINS

During the cell cycle, genomic stability requires accurate chromosome segregation. Errors in this process can cause aneuploidy, leading to tumorigenesis. To ensure faithful chromosome segregation, cells use the spindle assembly checkpoint (SAC) mechanism. However, in aneuploid cancer cells component...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Maachani, Uday, Scott, Tamalee, Hanson, Ryan, Zhao, Shuping, Celiku, Orieta, Shankavaram, Uma, Caplen, Natasha, Camphausen, Kevin, Tandle, Anita
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4218523/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou270.15
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