RT-18 TARGETING MPS1 ENHANCES RADIOSENSITIZATION OF HUMAN GLIOBLASTOMA BY MODULATING DNA REPAIR PROTEINS

During the cell cycle, genomic stability requires accurate chromosome segregation. Errors in this process can cause aneuploidy, leading to tumorigenesis. To ensure faithful chromosome segregation, cells use the spindle assembly checkpoint (SAC) mechanism. However, in aneuploid cancer cells component...

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Bibliografiske detaljer
Udgivet i:Neuro Oncol
Main Authors: Maachani, Uday, Scott, Tamalee, Hanson, Ryan, Zhao, Shuping, Celiku, Orieta, Shankavaram, Uma, Caplen, Natasha, Camphausen, Kevin, Tandle, Anita
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2014
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Abstracts
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4218523/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou270.15
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