Synthesis, Flow Cytometric Evaluation and Identification of Highly Potent Dipyridamole Analogs as Equilibrative Nucleoside Transporter 1 (ENT1) Inhibitors

Por Lin, Wenwei, Buolamwini, John K.
Publicado em 2007

Novel C(2)-Purine Position Analogs of Nitrobenzylmercaptopurine Riboside as Human Equilibrative Nucleoside Transporter 1 Inhibitors

Por Gupte, Amol, Buolamwini, John K.
Publicado em 2007

Constrained NBMPR Analogue Synthesis, Pharmacophore Mapping and 3D-QSAR Modeling of Equilibrative nucleoside Transporter 1 (ENT1) Inhibitory Activity

Por Zhu, Zhengxiang, Buolamwini, John K.
Publicado em 2008

A novel RNA variant of human concentrative nucleoside transporter 1 (hCNT1) that is a potential cancer biomarker

Por Wang, Chunmei, Buolamwini, John K.
Publicado no Exp Hematol Oncol (2019)

Homology Modeling of Human Concentrative Nucleoside Transporters (hCNTs) and Validation by Virtual Screening and Experimental Testing to Identify Novel hCNT1 Inhibitors

Por Kumar Deokar, Hemant, Barch, Hilaire Playa, Buolamwini, John K
Publicado no Drug Des (2017)

A Small-molecule Inhibitor of MDMX Activates p53 and Induces Apoptosis

Por Wang, Hongbo, Ma, Xujun, Ren, Shumei, Buolamwini, John K., Yan, Chunhong
Publicado em 2010

QSAR Studies of New Pyrido[3,4-b]indole Derivatives as Inhibitors of Colon and Pancreatic Cancer Cell Proliferation

Por Deokar, Hemantkumar, Deokar, Mrunalini, Wang, Wei, Zhang, Ruiwen, Buolamwini, John K.
Publicado no Med Chem Res (2018)

Quantitative structure-activity relationship studies on nitrofuranyl antitubercular agents

Por Hevener, Kirk E., Ball, David M., Buolamwini, John K., Lee, Richard E.
Publicado em 2008

Chemoprevention Activity of Dipyridamole in the MMTV-PyMT Transgenic Mouse Model of Breast Cancer

Por Wang, Chunmei, Schwab, Luciana P., Fan, Meiyun, Seagroves, Tiffany N., Buolamwini, John K.
Publicado em 2013

Inhibiting β-Catenin by β-Carboline-Type MDM2 Inhibitor for Pancreatic Cancer Therapy

Por Qin, Jiang-Jiang, Wang, Wei, Li, Xin, Deokar, Hemantkumar, Buolamwini, John K., Zhang, Ruiwen
Publicado no Front Pharmacol (2018)

Synthesis, Biological Evaluation and 3D-QSAR Studies of 3-Keto Salicylic Acid Chalcones and Related Amides as Novel HIV-1 Integrase Inhibitors

Por Sharma, Horrick, Patil, Shivaputra, Sanchez, Tino W., Neamati, Nouri, Schinazi, Raymond F., Buolamwini, John K.
Publicado em 2011

A quantitative LC-MS/MS method for determination of SP-141, a novel pyrido[b]indole anticancer agent, and its application to a mouse PK study

Por Nag, Subhasree, Qin, Jiang-Jiang, Patil, Shivaputra, Deokar, Hemantkumar, Buolamwini, John K., Wang, Wei, Zhang, Ruiwen
Publicado em 2014

Synthesis, docking, and biological studies of phenanthrene β-diketo acids as novel HIV-1 integrase inhibitors

Por Sharma, Horrick, Sanchez, Tino W., Neamati, Nouri, Detorio, Mervi, Schinazi, Raymond F., Cheng, Xiaolin, Buolamwini, John K.
Publicado em 2013

JKA97, a Novel Benzylidene Analog of Harmine, Exerts Anti-Cancer Effects by Inducing G1 Arrest, Apoptosis, and p53-Independent Up-Regulation of p21

Por Yang, Xinyi, Wang, Wei, Qin, Jiang-Jiang, Wang, Ming-Hai, Sharma, Horrick, Buolamwini, John K., Wang, Hui, Zhang, Ruiwen
Publicado em 2012

Inhibition of gastric tumor growth by a novel HSP90 inhibitor

Por Lu, Chunwan, Liu, Di, Jin, Jing, Deokar, Hemantkumar, Zhang, Yi, Buolamwini, John K., Yu, Xiaoming, Yan, Chunhong, Chen, Xiaoguang
Publicado em 2013

Development and validation of a rapid HPLC method for quantitation of SP-141, a novel pyrido[b]indole anticancer agent, and an initial pharmacokinetic study in mice

Por Nag, Subhasree, Qin, Jiang-Jiang, Voruganti, Sukesh, Wang, Ming-Hai, Sharma, Horrick, Patil, Shivaputra, Buolamwini, John K., Wang, Wei, Zhang, Ruiwen
Publicado no Biomed Chromatogr (2014)

Dilazep Analogues for the Study of Equilibrative Nucleoside Transporters 1 and 2 (ENT1 and ENT2)

Por Playa, Hilaire, Lewis, Timothy A., Ting, Amal, Suh, Byung-Chul, Muñoz, Benito, Matuza, Robert, Passer, Brent J., Schreiber, Stuart L., Buolamwini, John K.
Publicado no Bioorg Med Chem Lett (2014)

Synthesis, Biological Evaluation and Modeling Studies of New Pyrido[3,4-b]indole Derivatives as Broad-Spectrum Potent Anticancer Agents

Por Patil, Shivaputra A, Addo, James K, Deokar, Hemantkumar, Sun, Shan, Wang, Jin, Li, Wei, Suttle, D Parker, Wang, Wei, Zhang, Ruiwen, Buolamwini, John K
Publicado no Drug Des (2017)

Identification of a New Class of MDM2 Inhibitor That Inhibits Growth of Orthotopic Pancreatic Tumors in Mice

Por WANG, WEI, QIN, JIANG-JIANG, VORUGANTI, SUKESH, WANG, MING-HAI, SHARMA, HORRICK, PATIL, SHIVAPUTRA, ZHOU, JIANWEI, WANG, HUI, MUKHOPADHYAY, DEBABRATA, BUOLAMWINI, JOHN K., ZHANG, RUIWEN
Publicado em 2014

The pyrido[b]indole MDM2 inhibitor SP-141 exerts potent therapeutic effects in breast cancer models

Por Wang, Wei, Qin, Jiang-Jiang, Voruganti, Sukesh, Srivenugopal, Kalkunte S., Nag, Subhasree, Patil, Shivaputra, Sharma, Horrick, Wang, Ming-Hai, Wang, Hui, Buolamwini, John K., Zhang, Ruiwen
Publicado no Nat Commun (2014)