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Dilazep Analogues for the Study of Equilibrative Nucleoside Transporters 1 and 2 (ENT1 and ENT2)

As ENT inhibitors including dilazep have shown efficacy improving oHSV1 targeted oncolytic cancer therapy, a series of dilazep analogues was synthesized and biologically evaluated to examine both ENT1 and ENT2 inhibition. The central diamine core, alkyl chains, ester linkage and substituents on the...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Bioorg Med Chem Lett
Päätekijät: Playa, Hilaire, Lewis, Timothy A., Ting, Amal, Suh, Byung-Chul, Muñoz, Benito, Matuza, Robert, Passer, Brent J., Schreiber, Stuart L., Buolamwini, John K.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5695681/
https://ncbi.nlm.nih.gov/pubmed/25454272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2014.10.026
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