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QSAR Studies of New Pyrido[3,4-b]indole Derivatives as Inhibitors of Colon and Pancreatic Cancer Cell Proliferation

We have discovered a new class of pyrido[b]bindole derivatives that show potent and broad spectrum anticancer activity with IC(50) values down to submicromolar levels. Structure-activity relationship data acquired with the compounds as antiproliferative agents against several cancer cell lines, i.e....

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Detalhes bibliográficos
Publicado no:Med Chem Res
Main Authors: Deokar, Hemantkumar, Deokar, Mrunalini, Wang, Wei, Zhang, Ruiwen, Buolamwini, John K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6662939/
https://ncbi.nlm.nih.gov/pubmed/31360052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00044-018-2250-5
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