GPBA: a GPCR for bile acids and an emerging therapeutic target for disorders of digestion and sensation

per Lieu, T, Jayaweera, G, Bunnett, N W
Publicat 2014

A25 COLONIC PROTEASES EVOKE SUSTAINED PAIN SIGNALING VIA A NOVEL ENDOSOMAL PATHWAY IN NEURONS

per Jimenez-Vargas, N, Bunnett, N, Vanner, S
Publicat a J Can Assoc Gastroenterol (2018)

Regulatory mechanisms that modulate signalling by G-protein-coupled receptors.

per Böhm, S K, Grady, E F, Bunnett, N W
Publicat 1997

Interactions between neutral endopeptidase (EC 3.4.24.11) and the substance P (NK1) receptor expressed in mammalian cells.

per Okamoto, A, Lovett, M, Payan, D G, Bunnett, N W
Publicat 1994

A313 MUCOSAL PROTEASES FROM IBS PATIENTS PRODUCE LONG TERM HYPEREXCITABILITY IN NOCICEPTIVE DRG NEURONS BY ACTIVATING NOVEL INTRACELLULAR SIGNALING PATHWAYS

per Jiménez-Vargas, N N, Reed, D E, Bunnett, N, Vanner, S
Publicat a J Can Assoc Gastroenterol (2018)

A role for calcitonin gene-related peptide in protection against gastric ulceration.

per Gray, J L, Bunnett, N W, Orloff, S L, Mulvihill, S J, Debas, H T
Publicat 1994

Agonist-induced internalization of the substance P (NK1) receptor expressed in epithelial cells.

per Garland, A M, Grady, E F, Payan, D G, Vigna, S R, Bunnett, N W
Publicat 1994

β-Arrestin–Dependent Endocytosis of Proteinase-Activated Receptor 2 Is Required for Intracellular Targeting of Activated Erk1/2

per DeFea, K.A., Zalevsky, J., Thoma, M.S., Déry, O., Mullins, R.D., Bunnett, N.W.
Publicat 2000

The tyrosine kinase inhibitor bafetinib inhibits PAR2-induced activation of TRPV4 channels in vitro and pain in vivo

per Grace, M S, Lieu, T, Darby, B, Abogadie, F C, Veldhuis, N, Bunnett, N W, McIntyre, P
Publicat 2014

Delineation of the endocytic pathway of substance P and its seven-transmembrane domain NK1 receptor.

per Grady, E F, Garland, A M, Gamp, P D, Lovett, M, Payan, D G, Bunnett, N W
Publicat 1995

The proliferative and antiapoptotic effects of substance P are facilitated by formation of a β-arrestin-dependent scaffolding complex

per DeFea, K. A., Vaughn, Z. D., O'Bryan, E. M., Nishijima, D., Déry, O., Bunnett, N. W.
Publicat 2000

A213 A NOVEL PH-SENSITIVE OPIOID ANALGESIC THAT IS SELECTIVELY ACTIVATED IN ACIDIC INFLAMMATORY ENVIRONMENTS

per Yu, Y, Jiménez-Vargas, N N, Lopez Lopez, C D, Jaramillo Polanco, J O, Bunnett, N W, Vanner, S
Publicat a J Can Assoc Gastroenterol (2020)

Agonist-selective endocytosis of mu opioid receptor by neurons in vivo.

per Sternini, C, Spann, M, Anton, B, Keith, D E, Bunnett, N W, von Zastrow, M, Evans, C, Brecha, N C
Publicat 1996

ACTIVATION AND INTERNALIZATION OF THE μ-OPIOID RECEPTOR BY THE NEWLY DISCOVERED ENDOGENOUS AGONISTS, ENDOMORPHIN-1 AND ENDOMORPHIN-2

per McCONALOGUE, K., GRADY, E. F., MINNIS, J., BALESTRA, B., TONINI, M., BRECHA, N. C., BUNNETT, N. W., STERNINI, C.
Publicat a Neuroscience (1999)

Neutral endopeptidase (EC 3.4.24.11) terminates colitis by degrading substance P

per Sturiale, S., Barbara, G., Qiu, B., Figini, M., Geppetti, P., Gerard, N., Gerard, C., Grady, E. F., Bunnett, N. W., Collins, S. M.
Publicat 1999

Direct observation of substance P-induced internalization of neurokinin 1 (NK1) receptors at sites of inflammation.

per Bowden, J J, Garland, A M, Baluk, P, Lefevre, P, Grady, E F, Vigna, S R, Bunnett, N W, McDonald, D M
Publicat 1994

Mast cell tryptase regulates rat colonic myocytes through proteinase-activated receptor 2.

per Corvera, C U, Déry, O, McConalogue, K, Böhm, S K, Khitin, L M, Caughey, G H, Payan, D G, Bunnett, N W
Publicat 1997

Serine proteases and protease-activated receptor 2 mediate the proinflammatory and algesic actions of diverse stimulants

per Cattaruzza, F, Amadesi, S, Carlsson, J F, Murphy, J E, Lyo, V, Kirkwood, K, Cottrell, G S, Bogyo, M, Knecht, W, Bunnett, N W
Publicat 2014

A201 ENDOGENOUS OPIOIDS AND NANOPARTICLES TARGETING SIGNALING FROM DELTA OPIOID RECEPTORS IN ENDOSOMES INDUCE SUSTAINED INHIBITION OF NOCICEPTIVE AFFERENT NERVES INNERVATING THE IN...

per Jiménez-Vargas, N N, Yu, Y, Jaramillo Polanco, J O, Lopez Lopez, C D, Gong, J, Schmidt, B L, Bunnett, N W, Vanner, S
Publicat a J Can Assoc Gastroenterol (2020)

Canine bombesin-like gastrin releasing peptides stimulate gastrin release and acid secretion in the dog.

per Bunnett, N W, Clark, B, Debas, H T, Del Milton, R C, Kovacs, T O, Orloff, M S, Pappas, T N, Reeve, J R, Rivier, J E, Walsh, J H
Publicat 1985