Serine proteases and protease-activated receptor 2 mediate the proinflammatory and algesic actions of diverse stimulants

BACKGROUND AND PURPOSE: Although serine proteases and agonists of protease-activated receptor 2 (PAR2) cause inflammation and pain, the spectrum of proteases that are activated by proinflammatory and algesic stimuli and their contribution to inflammatory pain are uncertain. EXPERIMENTAL APPROACH: En...

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Detalhes bibliográficos
Main Authors: Cattaruzza, F, Amadesi, S, Carlsson, J F, Murphy, J E, Lyo, V, Kirkwood, K, Cottrell, G S, Bogyo, M, Knecht, W, Bunnett, N W
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2014
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4128045/
https://ncbi.nlm.nih.gov/pubmed/24749982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12738
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