Serine proteases mediate inflammatory pain in acute pancreatitis

Acute pancreatitis is a life-threatening inflammatory disease characterized by abdominal pain of unknown etiology. Trypsin, a key mediator of pancreatitis, causes inflammation and pain by activating protease-activated receptor 2 (PAR(2)), but the isoforms of trypsin that cause pancreatitis and pancr...

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Detalhes bibliográficos
Main Authors: Ceppa, Eugene P., Lyo, Victoria, Grady, Eileen F., Knecht, Wolfgang, Grahn, Sarah, Peterson, Anders, Bunnett, Nigel W., Kirkwood, Kimberly S., Cattaruzza, Fiore
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2011
Assuntos:
Pancreas
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3774216/
https://ncbi.nlm.nih.gov/pubmed/21436316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00305.2010
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