Structural basis for polymerase η–promoted resistance to the anticancer nucleoside analog cytarabine

par Rechkoblit, Olga, Choudhury, Jayati Roy, Buku, Angeliki, Prakash, Louise, Prakash, Satya, Aggarwal, Aneel K.
Publié dans Sci Rep (2018)

Structural insights into mutagenicity of anticancer nucleoside analog cytarabine during replication by DNA polymerase η

par Rechkoblit, Olga, Johnson, Robert E., Buku, Angeliki, Prakash, Louise, Prakash, Satya, Aggarwal, Aneel K.
Publié dans Sci Rep (2019)

Crystal Structure of Yeast DNA Polymerase ε Catalytic Domain

par Jain, Rinku, Rajashankar, Kanagalaghatta R., Buku, Angeliki, Johnson, Robert E., Prakash, Louise, Prakash, Satya, Aggarwal, Aneel K.
Publié 2014

Mechanism of error-free DNA synthesis across N1-methyl-deoxyadenosine by human DNA polymerase-ι

par Jain, Rinku, Choudhury, Jayati Roy, Buku, Angeliki, Johnson, Robert E., Prakash, Louise, Prakash, Satya, Aggarwal, Aneel K.
Publié dans Sci Rep (2017)

Human DNA polymerase η is pre-aligned for dNTP binding and catalysis

par Ummat, Ajay, Silverstein, Timothy D., Rinku, Jain, Buku, Angeliki, Johnson, Robert E., Prakash, Louise, Prakash, Satya, Aggarwal, Aneel K.
Publié 2011

An iron-sulfur cluster in the polymerase domain of yeast DNA polymerase ε

par Jain, Rinku, Vanamee, Eva S., Dzikovski, Boris G., Buku, Angeliki, Johnson, Robert E., Prakash, Louise, Prakash, Satya, Aggarwal, Aneel K.
Publié 2013

Structural basis for cisplatin DNA damage tolerance by human polymerase η during cancer chemotherapy

par Ummat, Ajay, Rechkoblit, Olga, Jain, Rinku, Choudhary, Jayati R., Johnson, Robert E., Silverstein, Timothy D., Buku, Angeliki, Lone, Samer, Prakash, Louise, Prakash, Satya, Aggarwal, Aneel K.
Publié 2012

Structure and Dynamics of the Second CARD of Human RIG-I Provide Mechanistic Insights into Regulation of RIG-I Activation

par Ferrage, Fabien, Dutta, Kaushik, Nistal-Villán, Estanislao, Patel, Jenish R., Sánchez-Aparicio, María T., De Ioannes, Pablo, Buku, Angeliki, Aseguinolaza, Gloria González, García-Sastre, Adolfo, Aggarwal, Aneel K.
Publié 2012