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Crystal Structure of Yeast DNA Polymerase ε Catalytic Domain
DNA polymerase ε (Polε) is a multi-subunit polymerase that contributes to genomic stability via its roles in leading strand replication and the repair of damaged DNA. Here we report the ternary structure of the Polε catalytic subunit (Pol2) bound to a nascent G:C base pair (Pol2(G:C)). Pol2(G:C) has...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3986358/ https://ncbi.nlm.nih.gov/pubmed/24733111 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0094835 |
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