Crystal Structure of Yeast DNA Polymerase ε Catalytic Domain

DNA polymerase ε (Polε) is a multi-subunit polymerase that contributes to genomic stability via its roles in leading strand replication and the repair of damaged DNA. Here we report the ternary structure of the Polε catalytic subunit (Pol2) bound to a nascent G:C base pair (Pol2(G:C)). Pol2(G:C) has...

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Detalhes bibliográficos
Main Authors: Jain, Rinku, Rajashankar, Kanagalaghatta R., Buku, Angeliki, Johnson, Robert E., Prakash, Louise, Prakash, Satya, Aggarwal, Aneel K.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3986358/
https://ncbi.nlm.nih.gov/pubmed/24733111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0094835
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