Crystal Structure of Yeast DNA Polymerase ε Catalytic Domain

DNA polymerase ε (Polε) is a multi-subunit polymerase that contributes to genomic stability via its roles in leading strand replication and the repair of damaged DNA. Here we report the ternary structure of the Polε catalytic subunit (Pol2) bound to a nascent G:C base pair (Pol2(G:C)). Pol2(G:C) has...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Jain, Rinku, Rajashankar, Kanagalaghatta R., Buku, Angeliki, Johnson, Robert E., Prakash, Louise, Prakash, Satya, Aggarwal, Aneel K.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2014
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3986358/
https://ncbi.nlm.nih.gov/pubmed/24733111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0094835
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