An iron-sulfur cluster in the polymerase domain of yeast DNA polymerase ε

DNA polymerase ε (Polε) is a multi-subunit polymerase that contributes to genomic stability via its roles in leading strand replication and the repair of damaged DNA. Polε from S. cerevisiae is composed of four subunits - Pol2, Dpb2, Dpb3, and Dpb4. Here, we report the presence of a [Fe-S] cluster d...

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Main Authors: Jain, Rinku, Vanamee, Eva S., Dzikovski, Boris G., Buku, Angeliki, Johnson, Robert E., Prakash, Louise, Prakash, Satya, Aggarwal, Aneel K.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4061903/
https://ncbi.nlm.nih.gov/pubmed/24144619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2013.10.015
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