Crystal Structure of Yeast DNA Polymerase ε Catalytic Domain

DNA polymerase ε (Polε) is a multi-subunit polymerase that contributes to genomic stability via its roles in leading strand replication and the repair of damaged DNA. Here we report the ternary structure of the Polε catalytic subunit (Pol2) bound to a nascent G:C base pair (Pol2(G:C)). Pol2(G:C) has...

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Detaylı Bibliyografya
Asıl Yazarlar: Jain, Rinku, Rajashankar, Kanagalaghatta R., Buku, Angeliki, Johnson, Robert E., Prakash, Louise, Prakash, Satya, Aggarwal, Aneel K.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2014
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3986358/
https://ncbi.nlm.nih.gov/pubmed/24733111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0094835
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