Structural basis for polymerase η–promoted resistance to the anticancer nucleoside analog cytarabine

por Rechkoblit, Olga, Choudhury, Jayati Roy, Buku, Angeliki, Prakash, Louise, Prakash, Satya, Aggarwal, Aneel K.
Publicado en Sci Rep (2018)

Structural insights into mutagenicity of anticancer nucleoside analog cytarabine during replication by DNA polymerase η

por Rechkoblit, Olga, Johnson, Robert E., Buku, Angeliki, Prakash, Louise, Prakash, Satya, Aggarwal, Aneel K.
Publicado en Sci Rep (2019)

Crystal Structure of Yeast DNA Polymerase ε Catalytic Domain

por Jain, Rinku, Rajashankar, Kanagalaghatta R., Buku, Angeliki, Johnson, Robert E., Prakash, Louise, Prakash, Satya, Aggarwal, Aneel K.
Publicado 2014

Mechanism of error-free DNA synthesis across N1-methyl-deoxyadenosine by human DNA polymerase-ι

por Jain, Rinku, Choudhury, Jayati Roy, Buku, Angeliki, Johnson, Robert E., Prakash, Louise, Prakash, Satya, Aggarwal, Aneel K.
Publicado en Sci Rep (2017)

Human DNA polymerase η is pre-aligned for dNTP binding and catalysis

por Ummat, Ajay, Silverstein, Timothy D., Rinku, Jain, Buku, Angeliki, Johnson, Robert E., Prakash, Louise, Prakash, Satya, Aggarwal, Aneel K.
Publicado 2011

An iron-sulfur cluster in the polymerase domain of yeast DNA polymerase ε

por Jain, Rinku, Vanamee, Eva S., Dzikovski, Boris G., Buku, Angeliki, Johnson, Robert E., Prakash, Louise, Prakash, Satya, Aggarwal, Aneel K.
Publicado 2013

Structural basis for cisplatin DNA damage tolerance by human polymerase η during cancer chemotherapy

por Ummat, Ajay, Rechkoblit, Olga, Jain, Rinku, Choudhary, Jayati R., Johnson, Robert E., Silverstein, Timothy D., Buku, Angeliki, Lone, Samer, Prakash, Louise, Prakash, Satya, Aggarwal, Aneel K.
Publicado 2012

Structure and Dynamics of the Second CARD of Human RIG-I Provide Mechanistic Insights into Regulation of RIG-I Activation

por Ferrage, Fabien, Dutta, Kaushik, Nistal-Villán, Estanislao, Patel, Jenish R., Sánchez-Aparicio, María T., De Ioannes, Pablo, Buku, Angeliki, Aseguinolaza, Gloria González, García-Sastre, Adolfo, Aggarwal, Aneel K.
Publicado 2012