Expanded GAA repeats impair FXN gene expression and reposition the FXN locus to the nuclear lamina in single cells

по Silva, Ana M., Brown, Jill M., Buckle, Veronica J., Wade-Martins, Richard, Lufino, Michele M.P.
Опубликовано в: Hum Mol Genet (2015)

Predicting the three-dimensional folding of cis-regulatory regions in mammalian genomes using bioinformatic data and polymer models

по Brackley, Chris A., Brown, Jill M., Waithe, Dominic, Babbs, Christian, Davies, James, Hughes, Jim R., Buckle, Veronica J., Marenduzzo, Davide
Опубликовано в: Genome Biol (2016)

A biophysical model for transcription factories

по Canals-Hamann, Ana Z, das Neves, Ricardo Pires, Reittie, Joyce E, Iñiguez, Carlos, Soneji, Shamit, Enver, Tariq, Buckle, Veronica J, Iborra, Francisco J
Опубликовано 2013

Coregulated human globin genes are frequently in spatial proximity when active

по Brown, Jill M., Leach, Joanne, Reittie, Joyce E., Atzberger, Ann, Lee-Prudhoe, Jane, Wood, William G., Higgs, Douglas R., Iborra, Francisco J., Buckle, Veronica J.
Опубликовано 2006

Robust CRISPR/Cas9 Genome Editing of the HUDEP-2 Erythroid Precursor Line Using Plasmids and Single-Stranded Oligonucleotide Donors

по Moir-Meyer, Gemma, Cheong, Pak Leng, Olijnik, Aude-Anais, Brown, Jill, Knight, Samantha, King, Andrew, Kurita, Ryo, Nakamura, Yukio, Gibbons, Richard J., Higgs, Douglas R., Buckle, Veronica J., Babbs, Christian
Опубликовано в: Methods Protoc (2018)

Association between active genes occurs at nuclear speckles and is modulated by chromatin environment

по Brown, Jill M., Green, Joanne, das Neves, Ricardo Pires, Wallace, Helen A.C., Smith, Andrew J.H., Hughes, Jim, Gray, Nicki, Taylor, Steve, Wood, William G., Higgs, Douglas R., Iborra, Francisco J., Buckle, Veronica J.
Опубликовано 2008

ATR-16 syndrome: mechanisms linking monosomy to phenotype

по Babbs, Christian, Brown, Jill, Horsley, Sharon W, Slater, Joanne, Maifoshie, Evie, Kumar, Shiwangini, Ooijevaar, Paul, Kriek, Marjolein, Dixon-McIver, Amanda, Harteveld, Cornelis L, Traeger-Synodinos, Jan, Wilkie, Andrew O M, Higgs, Douglas R, Buckle, Veronica J
Опубликовано в: J Med Genet (2020)

A tissue-specific self-interacting chromatin domain forms independently of enhancer-promoter interactions

по Brown, Jill M., Roberts, Nigel A., Graham, Bryony, Waithe, Dominic, Lagerholm, Christoffer, Telenius, Jelena M., De Ornellas, Sara, Oudelaar, A. Marieke, Scott, Caroline, Szczerbal, Izabela, Babbs, Christian, Kassouf, Mira T., Hughes, Jim R., Higgs, Douglas R., Buckle, Veronica J.
Опубликовано в: Nat Commun (2018)

Homozygous mutations in a predicted endonuclease are a novel cause of congenital dyserythropoietic anemia type I

по Babbs, Christian, Roberts, Nigel A., Sanchez-Pulido, Luis, McGowan, Simon J., Ahmed, Momin R., Brown, Jill M., Sabry, Mohamed A., Bentley, David R., McVean, Gil A., Donnelly, Peter, Gileadi, Opher, Ponting, Chris P., Higgs, Douglas R., Buckle, Veronica J.
Опубликовано 2013

Dynamics of the 4D genome during in vivo lineage specification and differentiation

по Oudelaar, A. Marieke, Beagrie, Robert A., Gosden, Matthew, de Ornellas, Sara, Georgiades, Emily, Kerry, Jon, Hidalgo, Daniel, Carrelha, Joana, Shivalingam, Arun, El-Sagheer, Afaf H., Telenius, Jelena M., Brown, Tom, Buckle, Veronica J., Socolovsky, Merav, Higgs, Douglas R., Hughes, Jim R.
Опубликовано в: Nat Commun (2020)

De novo and rare inherited mutations implicate the transcriptional coregulator TCF20/SPBP in autism spectrum disorder

по Babbs, Christian, Lloyd, Deborah, Pagnamenta, Alistair T, Twigg, Stephen R F, Green, Joanne, McGowan, Simon J, Mirza, Ghazala, Naples, Rebecca, Sharma, Vikram P, Volpi, Emanuela V, Buckle, Veronica J, Wall, Steven A, Knight, Samantha J L, Parr, Jeremy R, Wilkie, Andrew O M
Опубликовано 2014

Single-allele chromatin interactions identify regulatory hubs in dynamic compartmentalized domains

по Oudelaar, A. Marieke, Davies, James O.J., Hanssen, Lars L.P., Telenius, Jelena M., Schwessinger, Ron, Liu, Yu, Brown, Jill M., Downes, Damien J., Chiariello, Andrea M., Bianco, Simona, Nicodemi, Mario, Buckle, Veronica J., Dekker, Job, Higgs, Douglas R., Hughes, Jim R.
Опубликовано в: Nat Genet (2018)

Cohesin Disrupts Polycomb-Dependent Chromosome Interactions in Embryonic Stem Cells

по Rhodes, James D.P., Feldmann, Angelika, Hernández-Rodríguez, Benjamín, Díaz, Noelia, Brown, Jill M., Fursova, Nadezda A., Blackledge, Neil P., Prathapan, Praveen, Dobrinic, Paula, Huseyin, Miles K., Szczurek, Aleksander, Kruse, Kai, Nasmyth, Kim A., Buckle, Veronica J., Vaquerizas, Juan M., Klose, Robert J.
Опубликовано в: Cell Rep (2020)

High-resolution targeted 3C interrogation of cis-regulatory element organization at genome-wide scale

по Downes, Damien J., Beagrie, Robert A., Gosden, Matthew E., Telenius, Jelena, Carpenter, Stephanie J., Nussbaum, Lea, De Ornellas, Sara, Sergeant, Martin, Eijsbouts, Chris Q., Schwessinger, Ron, Kerry, Jon, Roberts, Nigel, Shivalingam, Arun, El-Sagheer, Afaf, Oudelaar, A. Marieke, Brown, Tom, Buckle, Veronica J., Davies, James O. J., Hughes, Jim R.
Опубликовано в: Nat Commun (2021)

Genetic and Functional Insights into CDA-I Prevalence and Pathogenesis

по Olijnik, Aude-Anaïs, Roy, Noémi, Scott, Caroline, Marsh, Joseph A, Brown, Jill, Lauschke, Karin, Ask, Katrine, Roberts, Nigel, Downes, Damien J., Brolih, Sanja, Johnson, Errin, Xella, Barbara, Proven, Melanie, Hipkiss, Ria, Ryan, Kate, Frisk, Per, Mäkk, Johan, Stattin, Evalena, Sadasivam, Nandini, McIlwaine, Louisa, Hill, Quentin A, Renella, Raffaele, Hughes, Jim R., Gibbons, Richard, Groth, Anja, McHugh, Peter J., Higgs, Douglas R, Buckle, Veronica J, Babbs, Christian
Опубликовано в: J Med Genet (2021)

Factors influencing success of clinical genome sequencing across a broad spectrum of disorders

по Taylor, Jenny C, Martin, Hilary C, Lise, Stefano, Broxholme, John, Cazier, Jean-Baptiste, Rimmer, Andy, Kanapin, Alexander, Lunter, Gerton, Fiddy, Simon, Allan, Chris, Aricescu, A. Radu, Attar, Moustafa, Babbs, Christian, Becq, Jennifer, Beeson, David, Bento, Celeste, Bignell, Patricia, Blair, Edward, Buckle, Veronica J, Bull, Katherine, Cais, Ondrej, Cario, Holger, Chapel, Helen, Copley, Richard R, Cornall, Richard, Craft, Jude, Dahan, Karin, Davenport, Emma E, Dendrou, Calliope, Devuyst, Olivier, Fenwick, Aimée L, Flint, Jonathan, Fugger, Lars, Gilbert, Rodney D, Goriely, Anne, Green, Angie, Greger, Ingo H., Grocock, Russell, Gruszczyk, Anja V, Hastings, Robert, Hatton, Edouard, Higgs, Doug, Hill, Adrian, Holmes, Chris, Howard, Malcolm, Hughes, Linda, Humburg, Peter, Johnson, David, Karpe, Fredrik, Kingsbury, Zoya, Kini, Usha, Knight, Julian C, Krohn, Jonathan, Lamble, Sarah, Langman, Craig, Lonie, Lorne, Luck, Joshua, McCarthy, Davis, McGowan, Simon J, McMullin, Mary Frances, Miller, Kerry A, Murray, Lisa, Németh, Andrea H, Nesbit, M Andrew, Nutt, David, Ormondroyd, Elizabeth, Oturai, Annette Bang, Pagnamenta, Alistair, Patel, Smita Y, Percy, Melanie, Petousi, Nayia, Piazza, Paolo, Piret, Sian E, Polanco-Echeverry, Guadalupe, Popitsch, Niko, Powrie, Fiona, Pugh, Chris, Quek, Lynn, Robbins, Peter A, Robson, Kathryn, Russo, Alexandra, Sahgal, Natasha, van Schouwenburg, Pauline A, Schuh, Anna, Silverman, Earl, Simmons, Alison, Sørensen, Per Soelberg, Sweeney, Elizabeth, Taylor, John, Thakker, Rajesh V, Tomlinson, Ian, Trebes, Amy, Twigg, Stephen RF, Uhlig, Holm H, Vyas, Paresh, Vyse, Tim, Wall, Steven A, Watkins, Hugh, Whyte, Michael P, Witty, Lorna, Wright, Ben, Yau, Chris, Buck, David, Humphray, Sean, Ratcliffe, Peter J, Bell, John I, Wilkie, Andrew OM, Bentley, David, Donnelly, Peter, McVean, Gilean
Опубликовано в: Nat Genet (2015)