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Association between active genes occurs at nuclear speckles and is modulated by chromatin environment

Genes on different chromosomes can be spatially associated in the nucleus in several transcriptional and regulatory situations; however, the functional significance of such associations remains unclear. Using human erythropoiesis as a model, we show that five cotranscribed genes, which are found on...

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Detalhes bibliográficos
Main Authors: Brown, Jill M., Green, Joanne, das Neves, Ricardo Pires, Wallace, Helen A.C., Smith, Andrew J.H., Hughes, Jim, Gray, Nicki, Taylor, Steve, Wood, William G., Higgs, Douglas R., Iborra, Francisco J., Buckle, Veronica J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2542471/
https://ncbi.nlm.nih.gov/pubmed/18809724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200803174
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