Focusing on the genetics of hearing: you ain't heard nothin' yet

Por Parkinson, Nick, Brown, Steve DM
Publicado em 2002

All systems GO for understanding mouse gene function

Por Holmes, Chris, Brown, Steve DM
Publicado em 2004

Mouse models as a tool to unravel the genetic basis for human otitis media

Por Zheng, Qing Yin, Hardisty-Hughes, Rachel, Brown, Steve D.M.
Publicado em 2006

Regulation of TGF-β signalling by Fbxo11, the gene mutated in the Jeff otitis media mouse mutant

Por Tateossian, Hilda, Hardisty-Hughes, Rachel E, Morse, Susan, Romero, Maria R, Hilton, Helen, Dean, Charlotte, Brown, Steve DM
Publicado em 2009

Otitis media in the Tgif knockout mouse implicates TGFβ signalling in chronic middle ear inflammatory disease

Por Tateossian, Hilda, Morse, Susan, Parker, Andrew, Mburu, Philomena, Warr, Nick, Acevedo-Arozena, Abraham, Cheeseman, Michael, Wells, Sara, Brown, Steve D.M.
Publicado em 2013

The Opdc missense mutation of Pax2 has a milder than loss-of-function phenotype

Por Cross, Sally H., McKie, Lisa, West, Katrine, Coghill, Emma L., Favor, Jack, Bhattacharya, Shoumo, Brown, Steve D.M., Jackson, Ian J.
Publicado em 2011

α-Synuclein levels modulate Huntington's disease in mice

Por Corrochano, Silvia, Renna, Maurizio, Carter, Sarah, Chrobot, Nichola, Kent, Rose, Stewart, Michelle, Cooper, Jason, Brown, Steve D.M., Rubinsztein, David C., Acevedo-Arozena, Abraham
Publicado em 2012

α-Synuclein levels modulate Huntington's disease in mice

Por Corrochano, Silvia, Renna, Maurizio, Carter, Sarah, Chrobot, Nichola, Kent, Rose, Stewart, Michelle, Cooper, Jason, Brown, Steve D.M., Rubinsztein, David C., Acevedo-Arozena, Abraham
Publicado em 2012

Association of the FBXO11 gene with COME/ROM in the Minnesota COME/ROM Family Study

Por Segade, Fernando, Daly, Kathleen A., Allred, Dax, Hicks, Pamela J., Cox, Miranda, Brown, Mark, Hardisty-Hughes, Rachel E., Brown, Steve D.M., Rich, Stephen S., Bowden, Donald W.
Publicado em 2006

IGF-1 receptor antagonism inhibits autophagy

Por Renna, Maurizio, Bento, Carla F., Fleming, Angeleen, Menzies, Fiona M., Siddiqi, Farah H., Ravikumar, Brinda, Puri, Claudia, Garcia-Arencibia, Moises, Sadiq, Oana, Corrochano, Silvia, Carter, Sarah, Brown, Steve D.M., Acevedo-Arozena, Abraham, Rubinsztein, David C.
Publicado em 2013

Mouse Models of NMNAT1-Leber Congenital Amaurosis (LCA9) Recapitulate Key Features of the Human Disease

Por Greenwald, Scott H., Charette, Jeremy R., Staniszewska, Magdalena, Shi, Lan Ying, Brown, Steve D.M., Stone, Lisa, Liu, Qin, Hicks, Wanda L., Collin, Gayle B., Bowl, Michael R., Krebs, Mark P., Nishina, Patsy M., Pierce, Eric A.
Publicado no Am J Pathol (2016)

Absence of Neuroplastin-65 Affects Synaptogenesis in Mouse Inner Hair Cells and Causes Profound Hearing Loss

Por Carrott, Leanne, Bowl, Michael R., Aguilar, Carlos, Johnson, Stuart L., Chessum, Lauren, West, Melissa, Morse, Susan, Dorning, Joanne, Smart, Elizabeth, Hardisty-Hughes, Rachel, Ball, Greg, Parker, Andrew, Barnard, Alun R., MacLaren, Robert E., Wells, Sara, Marcotti, Walter, Brown, Steve D.M.
Publicado no J Neurosci (2016)

Three Novel Pigmentation Mutants Generated by Genome-Wide Random ENU Mutagenesis in the Mouse

Por Tsipouri, Vicky, Curtin, John A., Nolan, Pat M., Vizor, Lucie, Parsons, Claire A., Clapham, Colin M., Latham, Ian D., Rooke, Lesley J., Martin, Jo E., Peters, Jo, Hunter, A. Jackie, Rogers, Derek, Rastan, Sohaila, Brown, Steve D.M., Fisher, Elizabeth M.C., Spurr, Nigel K., Gray, Ian C.
Publicado em 2004

Organization and Evolution of a Gene-Rich Region of the Mouse Genome: A 12.7-Mb Region Deleted in the Del(13)Svea36H Mouse

Por Mallon, Ann-Marie, Wilming, Laurens, Weekes, Joseph, Gilbert, James G.R., Ashurst, Jennifer, Peyrefitte, Sandrine, Matthews, Lucy, Cadman, Matthew, McKeone, Richard, Sellick, Chris A., Arkell, Ruth, Botcherby, Marc R.M., Strivens, Mark A., Campbell, R. Duncan, Gregory, Simon, Denny, Paul, Hancock, John M., Rogers, Jane, Brown, Steve D.M.
Publicado em 2004

Mutations in α-Tubulin Cause Abnormal Neuronal Migration in Mice and Lissencephaly in Humans

Por Keays, David A., Tian, Guoling, Poirier, Karine, Huang, Guo-Jen, Siebold, Christian, Cleak, James, Oliver, Peter L., Fray, Martin, Harvey, Robert J., Molnár, Zoltán, Piñon, Maria C., Dear, Neil, Valdar, William, Brown, Steve D.M., Davies, Kay E., Rawlins, J. Nicholas P., Cowan, Nicholas J., Nolan, Patrick, Chelly, Jamel, Flint, Jonathan
Publicado em 2007

Impaired Synaptic Plasticity and Motor Learning in Mice with a Point Mutation Implicated in Human Speech Deficits

Por Groszer, Matthias, Keays, David A., Deacon, Robert M.J., de Bono, Joseph P., Prasad-Mulcare, Shweta, Gaub, Simone, Baum, Muriel G., French, Catherine A., Nicod, Jérôme, Coventry, Julie A., Enard, Wolfgang, Fray, Martin, Brown, Steve D.M., Nolan, Patrick M., Pääbo, Svante, Channon, Keith M., Costa, Rui M., Eilers, Jens, Ehret, Günter, Rawlins, J. Nicholas P., Fisher, Simon E.
Publicado em 2008

MUTATIONS IN THE GABRB1 GENE PROMOTE ALCOHOL CONSUMPTION THROUGH INCREASED TONIC INHIBITION

Por Anstee, Quentin M., Knapp, Susanne, Maguire, Edward P., Hosie, Alastair M., Thomas, Philip, Mortensen, Martin, Bhome, Rohan, Martinez, Alonso, Walker, Sophie E., Dixon, Claire I., Ruparelia, Kush, Montagnese, Sara, Kuo, Yu-Ting, Herlihy, Amy, Bell, Jimmy D, Robinson, Iain, Guerrini, Irene, McQuillin, Andrew, Fisher, Elizabeth M.C., Ungless, Mark A., Gurling, Hugh M.D., Morgan, Marsha Y., Brown, Steve D.M., Stephens, David N., Belelli, Delia, Lambert, Jeremy J., Smart, Trevor G., Thomas, Howard C.
Publicado em 2013

Genome-wide association of multiple complex traits in outbred mice by ultra low-coverage sequencing

Por Nicod, Jérôme, Davies, Robert W., Cai, Na, Hassett, Carl, Goodstadt, Leo, Cosgrove, Cormac, Yee, Benjamin K, Lionikaite, Vikte, McIntyre, Rebecca E, Remme, Carol Ann, Lodder, Elisabeth M., Gregory, Jennifer S., Hough, Tertius, Joynson, Russell, Phelps, Hayley, Nell, Barbara, Rowe, Clare, Wood, Joe, Walling, Alison, Bopp, Nasrin, Bhomra, Amarjit, Hernandez-Pliego, Polinka, Callebert, Jacques, Aspden, Richard M., Talbot, Nick P, Robbins, Peter A, Harrison, Mark, Fray, Martin, Launay, Jean-Marie, Pinto, Yigal M., Blizard, David A., Bezzina, Connie R., Adams, David J, Franken, Paul, Weaver, Tom, Wells, Sara, Brown, Steve DM, Potter, Paul K, Klenerman, Paul, Lionikas, Arimantas, Mott, Richard, Flint, Jonathan
Publicado no Nat Genet (2016)

A comparative phenotypic and genomic analysis of C57BL/6J and C57BL/6N mouse strains

Por Simon, Michelle M, Greenaway, Simon, White, Jacqueline K, Fuchs, Helmut, Gailus-Durner, Valérie, Wells, Sara, Sorg, Tania, Wong, Kim, Bedu, Elodie, Cartwright, Elizabeth J, Dacquin, Romain, Djebali, Sophia, Estabel, Jeanne, Graw, Jochen, Ingham, Neil J, Jackson, Ian J, Lengeling, Andreas, Mandillo, Silvia, Marvel, Jacqueline, Meziane, Hamid, Preitner, Frédéric, Puk, Oliver, Roux, Michel, Adams, David J, Atkins, Sarah, Ayadi, Abdel, Becker, Lore, Blake, Andrew, Brooker, Debra, Cater, Heather, Champy, Marie-France, Combe, Roy, Danecek, Petr, di Fenza, Armida, Gates, Hilary, Gerdin, Anna-Karin, Golini, Elisabetta, Hancock, John M, Hans, Wolfgang, Hölter, Sabine M, Hough, Tertius, Jurdic, Pierre, Keane, Thomas M, Morgan, Hugh, Müller, Werner, Neff, Frauke, Nicholson, George, Pasche, Bastian, Roberson, Laura-Anne, Rozman, Jan, Sanderson, Mark, Santos, Luis, Selloum, Mohammed, Shannon, Carl, Southwell, Anne, Tocchini-Valentini, Glauco P, Vancollie, Valerie E, Westerberg, Henrik, Wurst, Wolfgang, Zi, Min, Yalcin, Binnaz, Ramirez-Solis, Ramiro, Steel, Karen P, Mallon, Ann-Marie, de Angelis, Martin Hrabě, Herault, Yann, Brown, Steve DM
Publicado em 2013

High-throughput discovery of novel developmental phenotypes

Por Dickinson, Mary E., Flenniken, Ann M., Ji, Xiao, Teboul, Lydia, Wong, Michael D., White, Jacqueline K., Meehan, Terrence F., Weninger, Wolfgang J., Westerberg, Henrik, Adissu, Hibret, Baker, Candice N., Bower, Lynette, Brown, James M., Caddle, L. Brianna, Chiani, Francesco, Clary, Dave, Cleak, James, Daly, Mark J., Denegre, James M., Doe, Brendan, Dolan, Mary E., Edie, Sarah M., Fuchs, Helmut, Gailus-Durner, Valerie, Galli, Antonella, Gambadoro, Alessia, Gallegos, Juan, Guo, Shiying, Horner, Neil R., Hsu, Chih-wei, Johnson, Sara J., Kalaga, Sowmya, Keith, Lance C., Lanoue, Louise, Lawson, Thomas N., Lek, Monkol, Mark, Manuel, Marschall, Susan, Mason, Jeremy, McElwee, Melissa L., Newbigging, Susan, Nutter, Lauryl M.J., Peterson, Kevin A., Ramirez-Solis, Ramiro, Rowland, Douglas J., Ryder, Edward, Samocha, Kaitlin E., Seavitt, John R., Selloum, Mohammed, Szoke-Kovacs, Zsombor, Tamura, Masaru, Trainor, Amanda G, Tudose, Ilinca, Wakana, Shigeharu, Warren, Jonathan, Wendling, Olivia, West, David B., Wong, Leeyean, Yoshiki, Atsushi, MacArthur, Daniel G., Tocchini-Valentini, Glauco P., Gao, Xiang, Flicek, Paul, Bradley, Allan, Skarnes, William C., Justice, Monica J., Parkinson, Helen E., Moore, Mark, Wells, Sara, Braun, Robert E., Svenson, Karen L., de Angelis, Martin Hrabe, Herault, Yann, Mohun, Tim, Mallon, Ann-Marie, Henkelman, R. Mark, Brown, Steve D.M., Adams, David J., Lloyd, K.C. Kent, McKerlie, Colin, Beaudet, Arthur L., Bucan, Maja, Murray, Stephen A.
Publicado no Nature (2016)