Mutagenic Effects of Ribavirin on Hepatitis E Virus—Viral Extinction versus Selection of Fitness-Enhancing Mutations

Por Todt, Daniel, Walter, Stephanie, Brown, Richard J. P., Steinmann, Eike
Publicado no Viruses (2016)

Hepacivirus NS3/4A Proteases Interfere with MAVS Signaling in both Their Cognate Animal Hosts and Humans: Implications for Zoonotic Transmission

Por Anggakusuma, Brown, Richard J. P., Banda, Dominic H., Todt, Daniel, Vieyres, Gabrielle, Steinmann, Eike, Pietschmann, Thomas
Publicado no J Virol (2016)

Genetic Diversity Underlying the Envelope Glycoproteins of Hepatitis C Virus: Structural and Functional Consequences and the Implications for Vaccine Design

Por Tarr, Alexander W., Khera, Tanvi, Hueging, Kathrin, Sheldon, Julie, Steinmann, Eike, Pietschmann, Thomas, Brown, Richard J. P.
Publicado no Viruses (2015)

Hepatitis C Virus Strain-Dependent Usage of Apolipoprotein E Modulates Assembly Efficiency and Specific Infectivity of Secreted Virions

Por Weller, Romy, Hueging, Kathrin, Brown, Richard J. P., Todt, Daniel, Joecks, Sebastian, Vondran, Florian W. R., Pietschmann, Thomas
Publicado no J Virol (2017)

Use of short tandem repeat fingerprinting to validate sample origins in hepatitis C virus molecular epidemiology studies

Por Edwards, Victoria C., McClure, C. Patrick, Brown, Richard J. P., Thompson, Emma, Irving, William L., Ball, Jonathan K.
Publicado em 2014

Naturally Occurring Antibodies That Recognize Linear Epitopes in the Amino Terminus of the Hepatitis C Virus E2 Protein Confer Noninterfering, Additive Neutralization

Por Tarr, Alexander W., Urbanowicz, Richard A., Jayaraj, Dhanya, Brown, Richard J. P., McKeating, Jane A., Irving, William L., Ball, Jonathan K.
Publicado em 2012

Hepatitis C Patient-Derived Glycoproteins Exhibit Marked Differences in Susceptibility to Serum Neutralizing Antibodies: Genetic Subtype Defines Antigenic but Not Neutralization Se...

Por Tarr, Alexander W., Urbanowicz, Richard A., Hamed, Mohamed R., Albecka, Anna, McClure, C. Patrick, Brown, Richard J. P., Irving, William L., Dubuisson, Jean, Ball, Jonathan K.
Publicado em 2011

A Diverse Panel of Hepatitis C Virus Glycoproteins for Use in Vaccine Research Reveals Extremes of Monoclonal Antibody Neutralization Resistance

Por Urbanowicz, Richard A., McClure, C. Patrick, Brown, Richard J. P., Tsoleridis, Theocharis, Persson, Mats A. A., Krey, Thomas, Irving, William L., Ball, Jonathan K., Tarr, Alexander W.
Publicado no J Virol (2016)

Identification of Conserved Residues in the E2 Envelope Glycoprotein of the Hepatitis C Virus That Are Critical for CD81 Binding

Por Owsianka, Ania M., Timms, Judith M., Tarr, Alexander W., Brown, Richard J. P., Hickling, Timothy P., Szwejk, Aleksandra, Bienkowska-Szewczyk, Krystyna, Thomson, Brian J., Patel, Arvind H., Ball, Jonathan K.
Publicado em 2006

Ion Channel Function and Cross-Species Determinants in Viral Assembly of Nonprimate Hepacivirus p7

Por Walter, Stephanie, Bollenbach, Alexander, Doerrbecker, Juliane, Pfaender, Stephanie, Brown, Richard J. P., Vieyres, Gabrielle, Scott, Claire, Foster, Richard, Kumar, Abhinav, Zitzmann, Nicole, Griffin, Stephen, Penin, François, Pietschmann, Thomas, Steinmann, Eike
Publicado no J Virol (2016)

Tracking HCV protease population diversity during transmission and susceptibility of founder populations to antiviral therapy

Por Khera, Tanvi, Todt, Daniel, Vercauteren, Koen, McClure, C. Patrick, Verhoye, Lieven, Farhoudi, Ali, Bhuju, Sabin, Geffers, Robert, Baumert, Thomas F., Steinmann, Eike, Meuleman, Philip, Pietschmann, Thomas, Brown, Richard J.P.
Publicado no Antiviral Res (2017)

In vivo evidence for ribavirin-induced mutagenesis of the hepatitis E virus genome

Por Todt, Daniel, Gisa, Anett, Radonic, Aleksandar, Nitsche, Andreas, Behrendt, Patrick, Suneetha, Pothakamuri Venkata, Pischke, Sven, Bremer, Birgit, Brown, Richard J P, Manns, Michael P, Cornberg, Markus, Bock, C Thomas, Steinmann, Eike, Wedemeyer, Heiner
Publicado no Gut (2016)

Intercompartmental Recombination of HIV-1 Contributes to env Intrahost Diversity and Modulates Viral Tropism and Sensitivity to Entry Inhibitors

Por Brown, Richard J. P., Peters, Paul J., Caron, Catherine, Gonzalez-Perez, Maria Paz, Stones, Leanne, Ankghuambom, Chiambah, Pondei, Kemebradikumo, McClure, C. Patrick, Alemnji, George, Taylor, Stephen, Sharp, Paul M., Clapham, Paul R., Ball, Jonathan K.
Publicado em 2011

Hepatitis C Virus Envelope Glycoprotein Fitness Defines Virus Population Composition following Transmission to a New Host

Por Brown, Richard J. P., Hudson, Natalia, Wilson, Garrick, Rehman, Shafiq Ur, Jabbari, Sara, Hu, Ke, Tarr, Alexander W., Borrow, Persephone, Joyce, Michael, Lewis, Jamie, Zhu, Lin Fu, Law, Mansun, Kneteman, Norman, Tyrrell, D. Lorne, McKeating, Jane A., Ball, Jonathan K.
Publicado em 2012

Immune protection against reinfection with nonprimate hepacivirus

Por Pfaender, Stephanie, Walter, Stephanie, Grabski, Elena, Todt, Daniel, Bruening, Janina, Romero-Brey, Inés, Gather, Theresa, Brown, Richard J. P., Hahn, Kerstin, Puff, Christina, Pfankuche, Vanessa M., Hansmann, Florian, Postel, Alexander, Becher, Paul, Thiel, Volker, Kalinke, Ulrich, Wagner, Bettina, Bartenschlager, Ralf, Baumgärtner, Wolfgang, Feige, Karsten, Pietschmann, Thomas, Cavalleri, Jessika M. V., Steinmann, Eike
Publicado no Proc Natl Acad Sci U S A (2017)

Analysis of Serine Codon Conservation Reveals Diverse Phenotypic Constraints on Hepatitis C Virus Glycoprotein Evolution

Por Brown, Richard J. P., Koutsoudakis, George, Urbanowicz, Richard A., Mirza, Deeman, Ginkel, Corinne, Riebesehl, Nina, Calland, Noémie, Albecka, Anna, Price, Louisa, Hudson, Natalia, Descamps, Véronique, Backx, Matthijs, McClure, C. Patrick, Duverlie, Gilles, Pecheur, Eve-Isabelle, Dubuisson, Jean, Perez-del-Pulgar, Sofia, Forns, Xavier, Steinmann, Eike, Tarr, Alexander W., Pietschmann, Thomas, Ball, Jonathan K.
Publicado em 2014

Flunarizine prevents hepatitis C virus membrane fusion in a genotype‐dependent manner by targeting the potential fusion peptide within E1

Por Perin, Paula M., Haid, Sibylle, Brown, Richard J.P., Doerrbecker, Juliane, Schulze, Kai, Zeilinger, Carsten, von Schaewen, Markus, Heller, Brigitte, Vercauteren, Koen, Luxenburger, Eva, Baktash, Yasmine M., Vondran, Florian W.R., Speerstra, Sietkse, Awadh, Abdullah, Mukhtarov, Furkat, Schang, Luis M., Kirschning, Andreas, Müller, Rolf, Guzman, Carlos A., Kaderali, Lars, Randall, Glenn, Meuleman, Philip, Ploss, Alexander, Pietschmann, Thomas
Publicado no Hepatology (2015)