Hepatitis C Virus Envelope Glycoprotein Fitness Defines Virus Population Composition following Transmission to a New Host

Genetic variability is a hallmark of RNA virus populations. However, transmission to a new host often results in a marked decrease in population diversity. This genetic bottlenecking is observed during hepatitis C virus (HCV) transmission and can arise via a selective sweep or through the founder ef...

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Bibliografski detalji
Glavni autori: Brown, Richard J. P., Hudson, Natalia, Wilson, Garrick, Rehman, Shafiq Ur, Jabbari, Sara, Hu, Ke, Tarr, Alexander W., Borrow, Persephone, Joyce, Michael, Lewis, Jamie, Zhu, Lin Fu, Law, Mansun, Kneteman, Norman, Tyrrell, D. Lorne, McKeating, Jane A., Ball, Jonathan K.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2012
Teme:
Pathogenesis and Immunity
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3486514/
https://ncbi.nlm.nih.gov/pubmed/22855498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01079-12
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