Hepatitis C Virus Envelope Glycoprotein Fitness Defines Virus Population Composition following Transmission to a New Host

Genetic variability is a hallmark of RNA virus populations. However, transmission to a new host often results in a marked decrease in population diversity. This genetic bottlenecking is observed during hepatitis C virus (HCV) transmission and can arise via a selective sweep or through the founder ef...

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Detalles Bibliográficos
Main Authors: Brown, Richard J. P., Hudson, Natalia, Wilson, Garrick, Rehman, Shafiq Ur, Jabbari, Sara, Hu, Ke, Tarr, Alexander W., Borrow, Persephone, Joyce, Michael, Lewis, Jamie, Zhu, Lin Fu, Law, Mansun, Kneteman, Norman, Tyrrell, D. Lorne, McKeating, Jane A., Ball, Jonathan K.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2012
Assuntos:
Pathogenesis and Immunity
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3486514/
https://ncbi.nlm.nih.gov/pubmed/22855498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01079-12
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